This product is an ELISA kit for the determination of Rat C5b-9 Terminal Complement Complex in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Rat C5b-9 Terminal Complement Complex as low as 13.5 pg/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Assay Type | Sandwich ELISA |
| Sensitivity | 13.5 pg/mL (31.25-2000 pg/mL) |
| Pack Size | 96 tests |
| Species Reactivity | Rat |
| Target | C5b-9 Complex |
| Cross Reactivity | No significant cross-reactions have been observed between Rat C5b-9 Terminal Complement Complex and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | The storage of components varies. Please refer to the instructions for details. |
| Introduction | C5b-9 terminal complement complex, also named as membrane attack complex (MAC), is a complex protein composed of the subunits C5b, C6, C7, C8 and several C9 molecules. The MAC is a structure typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is one of the effector proteins of the immune system. The MAC forms transmembrane channels, which disrupt the cell membrane of target cells, leading to cell lysis and death. |