This product is an ELISA kit for the determination of Rat C5b-9 Terminal Complement Complex in the samples of Plasma, Serum and Tissue Homogenates. It is highly sensitive and available for the detection of Rat C5b-9 Terminal Complement Complex as low as 0.39 ng/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Assay Type | Sandwich ELISA |
| Sensitivity | 0.39 ng/mL (1.56-100 ng/mL) |
| Pack Size | 96 tests |
| Species Reactivity | Rat |
| Target | C5b-9 Complex |
| Cross Reactivity | No significant cross-reactions have been observed between Rat C5b-9 Terminal Complement Complex and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | Store at 4°C/-20°C, please refer to the instructions for details. |
| Introduction | C5b-9 terminal complement complex, also named as membrane attack complex (MAC), is a complex protein composed of the subunits C5b, C6, C7, C8 and several C9 molecules. The MAC is a structure typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is one of the effector proteins of the immune system. The MAC forms transmembrane channels, which disrupt the cell membrane of target cells, leading to cell lysis and death. |
Well-packaged, with clear instructions and all necessary componentsExcellentThe kit was easy to use, and the quality of the data was exceptional. The standard curve was very reproducible, which made quantification straightforward. The results were consistent with previous studies, validating the kit's performance. However, I would appreciate more comprehensive troubleshooting guidelines in the manual.
WorthwhileExcellentWe've used the CTK-360 ELISA kit extensively in our lab for evaluating complement activity in rat models. The assay is straightforward, and the quality control measures are top-notch. The sensitivity of the kit has been particularly useful in detecting subtle changes in complement levels, which is crucial for our ongoing projects.
The performance has been consistent, and the assay protocol is user-friendlyExcellentWe've noticed a significant improvement in data accuracy compared to previous kits we've used. The calibration curves are very reliable, and the overall value of the kit justifies its price. It's an essential component of our experimental setup.
It's a reliable kit for detailed complement analysisExcellentIt delivers precise and reliable measurements of complement activation products, which are crucial for our research on autoimmune diseases. The kit's comprehensive manual and detailed troubleshooting guide have been very helpful.
It has consistently provided high-quality resultsExcellentThe assay is quite sensitive and specific, allowing us to accurately measure complement levels even in complex samples. It's a valuable tool for our research.