SB290157 (Trifluoroacetate)(Cat#: CTI-001)

Name: SB290157 (Trifluoroacetate)
SKU: CTI-001
Rating: 5 (1 reviews)

This product is a potent C3a receptor antagonist, it selectively inhibits C3aR with the IC50 of 200 nM.

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CAS No.	1140525-25-2
Formula	C₂₄H₂₉F₃N₄O₆
Molecular Weight	526.51
SMILES	N=C(N)NCCC[C@@H](C(O)=O)NC(COCC(C1=CC=CC=C1)C2=CC=CC=C2)=O.OC(C(F)(F)F)=O
IC50	IC50: 200 Nm
Purity	95%
Solubility	DMSO: 125 mg/mL (Need ultrasonic)
Storage	Store at -4°C for short term; at -20 °C for long-term storage.
Target	C3aR
Introduction	The anaphylatoxin C3a, a potent chemotactic peptide and inflammatory mediator, binds to and activates a G-protein-coupled receptor. Molecular cloning of the C3aR has facilitated the identification of the non-peptide C3aR antagonists.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.