Bioconjugation

Site-Specific Conjugation Platform

What is Site-specific Conjugation?

Conventional conjugation methods generate a variety of heterogeneous. Site-specific conjugation overcomes this disadvantage by linking molecules based on specific sites. We are dedicated to delivering tailored conjugation services that cater to your diverse research requirements.

Fig. 1 The application of the site-specific conjugation methods. (Creative Biolabs Original)Fig. 1 The application of the site-specific conjugation methods.

Multiple Conjugation Methods

Amino Acids Sites

We can provide two conjugate services that depend on amino acid sites for greater homogeneity. The first is based on natural or engineered modifications of specific amino acids, such as cysteine and glutamine; the other is based on the insertion of amino acids, including selenocysteine, and the unnatural amino acid, etc.

Glycans

This approach employs a glycotransferases to achieve conjugation at sites far from amino acid residues. Based on this technology, we can selectively transfer chemically reactive sugar to any lipid or protein that contains glycosylation sites.

There are several monosaccharides present at the non-reactive end of the glycans that we can use for conjugating, including fucose (Fuc), galactose, sialic acid (SA), etc.

Short Peptide Tags

We can add short peptide tags with 4-6 amino acid residues to provide you with conjugate services, such as glutamine tags (LLQG).

Our Custom Bioconjugation Services

Linker Development

We have an extensive linker library and can also customize linkers to suit your needs.

Biomolecules

Protein & Antibody Oligonucleotide
Nucleic Acids/Oligonucleotides Oligosaccharide
Small Molecule Liposome
Bacteria Bead & Particle
Virus Metal Chelates
Bacteriophage PEG
Fluorescent Photoaffinity Label

Custom Bioconjugation

We have extensive experience in bioconjugation, including these biomolecules on the right.

Ligand Screening

With ligand screening through bioconjugate technology, we can help you with your drug discovery.

Application

Based on conjugating, we can meet your diverse research needs, including Discovery of Biological Interactions, Biochemical Assays, Drug Delivery, Imaging In Vivo, PEGylation and Industrial.

Creative Biolabs holds a prominent position in the field of bioconjugate, with our experts possessing years of experience in conjugation. Based on our unique Site-specific Conjugation Platform, we offer comprehensive custom services to assist your project throughout the entire process, from preclinical research to commercial-scale production. Should you express interest in our services, please feel free to contact us for comprehensive information.

For research use only. Not intended for any clinical use.

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