BCX 1470(Cat#: CTI-015)

This product is a potent and selective factor D antagonist, it inhibits factor D with the IC50 of 96 nM. It also inhibits C1s with the IC50 of 1.6 nM.

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Specifications
CAS No. 217099-43-9
Formula C₁₄H₁₀N₂O₂S₂
Molecular Weight 302.37
SMILES N=C(C1=CC2=CC=C(OC(C3=CC=CS3)=O)C=C2S1)N
IC50 IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin)
Purity 95%
Storage Store at -4°C for short term; at -20 °C for long-term storage.
Target Factor D
Introduction The Factor D is a member of the trypsin family of peptidases. It is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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