Mouse Anti-Human C5b-9 Monoclonal Antibody (CTJS-605)(Cat#: CTA-012)

This product is an unconjugated anti-Human Complement C5b-9 Monoclonal antibody (CTJS-605) generated from the Mouse. The antibody can be used for ELISA; IF; IHC; WB.

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Specifications
Clonality Monoclonal
Clone CTJS-605
Host Animal Mouse
Isotype IgG2aκ
Immunogen Purified human complement component C5b-9
Species Reactivity Human; Baboon; Horse; Porcine
Applications ELISA; IF; IHC; WB
Application Notes ELISA: 1:100-1:2000
IHC: 1:10-1:500
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human, Baboon, Horse, Porcine both membrane-bound MAC and fluid phase SC5b-9 complexes.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 25; 100 µg
Storage 4°C, store in dark
Type Primary Antibody
Target
Target Name C5b-9 complex
Alternative Names Membrane attack complex; MAC; Terminal complement complex; TCC; scC5b-9
Information
Introduction C5b-9 complex is composed of the complement components C5b, C6, C7, C8 and several C9 molecules. It is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector of the immune system. Assembly of the MAC leads to pores that disrupt the cell membrane of target cells, leading to cell lysis and death.

Customer Review

Excellent for immunofluorescence applications
Excellent
We used it to stain tissue sections and were very pleased with the clear and bright signals. The antibody binds specifically to its target without any non-specific background, which is crucial for our research on complement-mediated tissue damage.
It worked exceptionally well
Excellent
In our recent study on chronic inflammatory diseases, the antibody has proven to be a reliable tool. We used it for Western blotting and found it to be very effective. The bands were sharp and specific, allowing us to accurately quantify the C5b-9 complex levels in our samples.
This antibody has been an invaluable resource for our ELISA assays
Excellent
We've used it to quantify C5b-9 levels in patient serum samples, and the results have been highly consistent and reliable. The antibody's sensitivity allows for accurate detection even at low concentrations.
It's a high-quality product that we will continue to use
Excellent
In our lab, we've used this antibody for immunofluorescence and were extremely satisfied with its performance. The staining was clear and specific, which helped us visualize the C5b-9 complex in various cell types.
I am very satisfied with its performance
Excellent
This antibody has proven to be very effective in Western blotting. The bands were clear and specific, with minimal background noise. It has helped us accurately quantify the C5b-9 complex in various experimental conditions.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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