PMX 205(Cat#: CTI-003)

This product is a potent C5a receptor antagonist and also used as an anti-inflammatory drug.

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Specifications
CAS No. 514814-49-4
Formula C₄₅H₆₂N₁₀O₆
Molecular Weight 839.04
Sequence XPXWR
(Modifications: X-1 = N2-(1-Oxo-3-phenylpropyl)-Orn, X-3 = D-Cha, Lactam bridge: Orn-1 to Arg-5)
SMILES O=C([C@H](NC([C@@]1([H])N(CCC1)C([C@](NC(CCC2=CC=CC=C2)=O)([H])CCCNC([C@H](CCCNC(N)=N)NC3=O)=O)=O)=O)CC4CCCCC4)N[C@@]3([H])CC5=CNC6=CC=CC=C56
Purity 95%
Solubility Soluble in DMSO
Storage Store at -20°C for short term; at -80 °C for long-term storage.
Target C5aR
Introduction The C5a receptor also known as C5AR1 or CD88 (Cluster of Differentiation 88), is a G protein-coupled receptor for C5a. It functions as a complement receptor. C5a receptor modulates inflammatory responses, obesity, development and cancers
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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