This product is a potent C5a receptor antagonist, it inhibits C5aR with the Ki value of 2.2 nM.
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CAS No. | 405098-33-1 |
Formula | C₃₀H₃₇ClN₂O₂ |
Molecular Weight | 493.08 |
SMILES | O=C(C1CCCC2=C1C=C(OC)C=C2)N(CC3=CC=C(N(C)C)C=C3)C4=CC=C(C(C)C)C=C4.[H]Cl |
IC50 | IC50: 2.2 nM |
Purity | 98% |
Solubility | DMSO :> 28 mg/mL (56.79 mM) |
Storage | Store at -4°C for short term; at -20 °C for long-term storage. |
Target | C5aR |
Introduction | The C5a receptor also known as C5AR1 or CD88 (Cluster of Differentiation 88), is a G protein-coupled receptor for C5a. It functions as a complement receptor. C5a receptor modulates inflammatory responses, obesity, development and cancers |