C1QB

Clear All
Host Animal Mouse
Specie Reactivity Human
Isotype IgG
Applications WB; IHC
Host Animal Rabbit
Specie Reactivity Human
Isotype IgG
Applications WB; IHC
Host Animal Rabbit
Specie Reactivity Human
Antibody Clone CTJS-215
Isotype IgG
Applications WB; ELISA
Host Animal Rabbit
Specie Reactivity Human
Antibody Clone CTJS-848
Isotype IgG
Applications ICC; WB; IHC
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P; PA
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Host Animal Mouse
Specie Reactivity Human
Antibody Clone TJL-11
Isotype IgG1 Kappa
Applications IHC; IHC-P
Specie Reactivity Human
Sensitivity 0.65 pg/mL (1.95-2000 pg/mL)
Applications ELISA
Specie Reactivity Mouse
Sensitivity 3.125 ng/mL (2.5-800 ng/mL)
Applications ELISA
Specie Reactivity Rat
Sensitivity 0.64 ng/mL (1.56-100 ng/mL)
Applications ELISA
Specie Reactivity Human
Sensitivity 15.1 pg/mL (31.2-2,000 pg/mL)
Applications ELISA
Clear All
Specie Reactivity Human
Type Recombinant Protein Antigen
Expression Host E. Coli
Applications AC
Specie Reactivity Human
Type Recombinant Protein
Expression Host Wheat Germ (in vitro)
Applications WB; ELISA; PA; AP
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host Yeast
Applications WB; ELISA
Specie Reactivity Mouse
Type Recombinant Protein
Expression Host E.coli/Mammalian cell/Baculovirus
Applications WB; ELISA
Specie Reactivity Rat
Type Recombinant Protein
Expression Host Yeast
Applications WB; ELISA
Specie Reactivity Rat
Type Recombinant Protein
Expression Host E.coli/Mammalian cell/Baculovirus
Applications WB; ELISA
Specie Reactivity Human
Type Recombinant Protein
Expression Host E.coli
Applications WB; Immunogen
Clear All
Specie Reactivity Mammalian
Purity >90%
Applications Blocking; IHC; WB
Specie Reactivity Human
Purity >90%
Applications Blocking; IHC; WB
Specie Reactivity Human
Purity >90%
Applications Blocking; WB
Specie Reactivity Human
Purity >90%
Applications Blocking
Specie Reactivity Human; Rat
Purity >85%
Applications Blocking
Specie Reactivity Human; Rat
Purity >85%
Applications Blocking
Specie Reactivity Human
Species of Lysate 293T Cells
Application Western Blotting (WB)
Specie Reactivity Human
Species of Lysate Baculovirus infected Insect Cells
Application Positive Control (PC); Western Blotting (WB)
Clear All
Specie Reactivity Human
Type Expression Plasmid
Vector pCMV6-Entry
Tag Myc-DDK
Specie Reactivity Human
Type Expression Plasmid
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Human
Type Expression Plasmid
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Human
Type Lentiviral Particle
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Human
Type Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Human
Type Expression Plasmid
Vector pCMV6-AC-GFP
Tag GFP
Specie Reactivity Human
Type Expression Plasmid
Vector pCMV6-XL4
Specie Reactivity Human
Type Expression Plasmid
Vector pCMV6-AC
Specie Reactivity Mouse
Type Expression Plasmid
Vector pCMV6-AC-GFP
Tag GFP
Specie Reactivity Mouse
Type Expression Plasmid
Vector pCMV6-Entry
Tag Myc-DDK
Specie Reactivity Mouse
Type Expression Plasmid
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Mouse
Type Expression Plasmid
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Mouse
Type Lentiviral Particle
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Mouse
Type Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
Tag GFP
Specie Reactivity Mouse
Type Expression Plasmid
Vector PCMV6-Kan/Neo
Specie Reactivity Rat
Type Expression Plasmid
Vector pCMV6-Entry
Tag Myc-DDK
Specie Reactivity Rat
Type Expression Plasmid
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Rat
Type Expression Plasmid
Vector pLenti-C-mGFP-P2A-Puro
Tag mGFP
Specie Reactivity Rat
Type Lentiviral Particle
Vector pLenti-C-Myc-DDK-P2A-Puro
Tag Myc-DDK
Specie Reactivity Rat
Type Lentiviral Particle
Vector pLenti-C-mGFP-P2A-Puro
Tag GFP
Specie Reactivity Rat
Type Expression Plasmid
Vector pCMV6-Entry
Product List Background

Background

Human complement C1q subcomponent subunit B (C1QB) is a 25 kDa polypeptide chain with 253 amino acids. Similar to C1QA, C1QB consists of a collagen-like ‘stalk’ at the N terminus and a globular ‘head’ at the C terminal. Human complement C1q is a protein complex composed of six heterotrimers, each of which contains a C1QA, a C1QB, and a C1QC chain. Each heterotrimer is noncovalently linked to each other, and in the heterotrimer, there are three polypeptide chains are connected by disulfide bonds. Thus, the C-terminal portion of these chains in each heterotrimer form the globular ‘head’ of complement C1q (gC1q), and the N- terminal sequences form the collagen-like region of complement C1q (cC1q).

As a critical component of complement C1q, C1QB expression is directly related to the function of C1q and complement classical pathway activation. Diseases associated with C1QB abnormity mainly include C1q deficiency, autoimmune diseases, immunodeficiency, and Alzheimer’s disease.

Fig. 1 Structure and assembly of C1QB subunit. (Ain et al., 2021)Fig. 1 Structure and assembly of C1QB subunit.1

Reference

  1. Ain, Danyaal, et al. "The role of complement in the tumor microenvironment." Faculty Reviews 10 (2021).
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For Research Use Only.