Stem Cell-derived Exosome Application
- MSC from iPSC Source
Scientists have utilized induced pluripotent stem cells (iPSCs) to generate differentiated mesenchymal stem cells (iMSCs). This approach is favored due to the extensive scalability and robust cell differentiation capabilities of iPSCs. iMSCs are highly sought-after for their adhibitions in exosome (Exo) extraction and Exo therapy research. Creative Biolabs has outlined the benefits and uses of iMSCs-derived Exos (iMSCs-Exos), playing a pivotal role in advancing the therapeutic potential of iMSCs-Exos.
Fig.1 Derivation of MSCs from iPSCs.1,2
Induced Pluripotent Stem Cell-derived Exosomes (iMSCs-Exos) Benefits
MSCs are present in miscellaneous tissues, including fat, amniotic membrane, amniotic fluid, dental pulp, placenta, skin, and menstrual blood. Each of these MSCs possesses unique differentiation pathways. Scientists have leveraged this diversity by effectively differentiating iPSCs into iMSCs. However, the treatment of iMSCs poses several restrictions. Alternatively, iMSCs-Exos have emerged as a solution to circumvent these issues.
iMSC-Exos Applied to Therapy Due to Their Benefits
iMSCs-Exos have proved encouraging outcomes in preclinical investigations, indicating their latent force as a therapeutic choice for various diseases.
In summary, iMSCs-Exos offer immense potential across diverse medical domains. They possess inherent advantages as natural nanoparticles, enabling them to encapsulate various therapeutic molecules, and can be readily engineered to target specific cells or tissues. However, additional research is required to comprehensively comprehend their capabilities and advance the development of safe and efficacious treatments. Creative Biolabs is actively focusing on the research of iMSCs-Exos and can provide customers with Exo one-stop service. If you are interested in stem cell-derived Exos including iMSCs-Exos, please contact us.
References
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Zhao, C.; Ikeya, M. Generation and applications of induced pluripotent stem cell-derived mesenchymal stem cells. Stem Cells Internationa. 2018, 2018:9601623.
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under Open Access license CC BY 4.0, without modification.
For Research Use Only. Cannot be used by patients.
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