Induced pluripotent stem cells-derived exosomes (iPSC-Exos) have shown promise in miscellaneous medicinal
applications due to their ability to carry bioactive molecules and promote tissue repair and regeneration. Creative Biolabs also pays attention to the medicinal feasibility of iPSC-Exos and can help
customers tap the value of iPSC-Exos by providing strong technology and professional knowledge.
iPSCs are a major discovery in biomedicine, derived from adult cells reprogrammed to a multipurpose state. This
makes it possible to differentiate into any type of cell in the body, making it an attractive tool for regenerative
medicine and drug development. However, despite the enormous feasibility of iPSCs, their applications are not
without limitations. A major concern is the risk of tumor formation due to their multipurpose nature. In addition,
the reprogramming and differentiation efficiencies of different cell lines vary widely, making it difficult to
obtain consistent results. Furthermore, the high cost and time required to produce iPSCs limits their widespread use
in clinical settings. These restrictive issues have forced researchers to find replacements for iPSCs. Exos secreted
by iPSCs (iPSC-Exos) have been found to carry many maternally derived bioactive substances and have recently become
a promising tool in the biomedical field due to their many benefits over conventional iPSC therapy.
These unique benefits make iPSC-Exos a promising tool for the development of new effective therapies.
Fig.1 Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing.1,2
iPSC-Exos Applied to Therapy Due to Their Benefits
Researchers are actively investigating the feasibility of iPSC-Exos as a non-invasive and cell-free alternative to
stem cell therapy. However, further studies are needed to fully understand their mechanisms of action and optimize
their therapeutic effects. In the professional services offered by Creative Biolabs, you can
research these burning questions. Please contact us and clarify your specific
goals.
References
Bo, Y.; et al. Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing through miR-762 mediated promotion of keratinocytes and endothelial cells migration. Journal of Nanobiotechnology. 2022, 20(1):291.
under Open Access license CC BY 4.0, without modification.
Fig.1 Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing.1,2
