Through our years of expertise in complement system research, Creative Biolabs steadily builds specific platforms and reliable methodologies. We can give extensive and personalized service to our international clients in the field of complement systems.
Complement component 3 (C3) is a protein contributing to the innate immunity of the immune system and is encoded by the C3 gene on human chromosome 19. Activated forms of C2 and C4 consist of the heterodimer C3-convertase, also known as C4b2a, which can proteolytically process C3 to generate mature proteins C3a and C3b. C3 is essential for the complement system's activation. A hemolytic assay is a useful option for assessing C3 activity in the complement system, which can be used to assess the potency and toxicity of various compounds and to quantify this capability by lysing red blood cells in response to the chemical.
Fig.1 Hemolytic assay protocol for C3.
Creative Biolabs has focused on complement systems for decades and summarized well-defined methodology in this field. We still have the advanced experimental equipment and the perfect experimental platforms to meet and tailor all your demands for complement system research. For details about your project involving complement systems, feel free to contact us.