Recombinant Human Dystroglycan 1, Wheat germ (CAT#: GP05-209J)

Product Overview	Recombinant Human Dystroglycan 1 (AAH12740) was produced using Wheat germ cell-free expression system. Measured by its binding ability in a functional ELISA.
Biological Activity	Measured by its binding ability in a functional ELISA.
Source	Wheat germ cell-free expression system
Species	Human
Purity	>90%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	DAG1
Full Name	Dystroglycan 1
Gene ID	1605
Uniprot ID	Q14118
Accession Number	AAH12740
Background	This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
Alternate Names	Dystroglycan 1; Dystrophin-associated glycoprotein-1; Dystrophin-associated glycoprotein 1; Alpha-Dystroglycan; Beta-Dystroglycan; MDDGC7; 156DAG; MDDGC9; AGRNR; A3A; DAG