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1 mg | ||
2 mg | ||
5 mg |
Product Overview | Recombinant Human DAG1 protein (NP_001159400.2) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites. |
Source | Glycoengineered Mannose-5 Pichia pastoris |
Species | Human |
Tag | His-tag, FC-tag |
Purity | >90%, determined by SDS-PAGE. |
Endotoxin Level | Regular batch |
Conjugation | None |
Target | DAG1 |
Full Name | Dystroglycan 1 |
Gene ID | 1605 |
Uniprot ID | Q14118 |
Accession Number | NP_001159400.2 |
Background | This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. |
Alternate Names | Dystroglycan 1 (Dystrophin-Associated Glycoprotein 1); Dystrophin-Associated Glycoprotein-1; Dystrophin-Associated Glycoprotein 1; Alpha-Dystroglycan; Beta-Dystroglycan; MDDGC7; 156DAG; MDDGC9; AGRNR; A3A; DAG |