Key Details
| Catalog | MAS-0124-YJ15 |
| Applications | ELISA; WB; Neut; FuncS |
| Host | Human |
| Reactivity | B. anthracis |
| Clonality | Monoclonal |
| Conjugations | Conjugation could be customized |
Overview
Properties
Target
Overview
| Description | All the four anti-LF clones have human IgG constant region. Clone hK07 is a Chimeric (mouse/human) monoclonal IgG recognizes B. anthracis Anthrax LF. PMLF is a fully human IgG1 kappa. H1KE2 and H13KE3 are chimeric (monkey/human IgGs H13KE3 has a affinity of ~7 nM to LF. |
| Reactivity | B. anthracis |
| Applications | ELISA; WB; Neut; FuncS |
| Host | Human |
| Immunogen | Bacillus anthracis Lethal Factor (LF) |
| Isotype |
hK07: Chimeric (mouse/human) IgG4 PMLF: Human IgG1 kappa H1KE2 & H13KE3: Chimeric (monkey/human) IgG1 |
| Clonality | Monoclonal |
| Clone | hK07; PMLF; H1KE2; H13KE3 |
| Dilutions | ELISA: 0.1-1000 ng/mL |
Properties
| Expression Host | HEK293F/CHO |
| Conjugations | Conjugation could be customized |
| Purification | Protein A/G affinity purified is the regular method |
| Purity | SDS-PAGE> 95% |
| Endotoxin Level | Endotoxin level could be customized |
| Form | Liquid (frequently-used) or lyophilized |
| Concentration | About 1mg/ml. There are differences between batches. Special concentration could be customized. |
| Sterility | 0.2 μM filtered |
| Buffer | See the Datasheet |
| Storage | See the Datasheet |
Target
| Target | B. anthracis Anthrax LF |
| Alternative Names | Anthrax lethal factor; LF; Anthrax LF; anthrax lethal toxin; LF; B. anthracis; Bacillus anthracis |
| Introduction | Anthrax toxin is a key virulence factor of anthrax, the chemical composition of three proteins: protective antigen (PA), lethal factor (LF) and edema factor (EF). LF or EF alone without toxicity, PA-LF complexes were formed after the PA and LF binding, called lethal toxin (Lethal Toxin, LeTx). |
| Organism | Bacteria |
| Related Disease | Anthrax |
| Infections Route | Cutaneous; Inhalation; Gastrointestinal; Injection |
Online Inquiry