Key Details
| Catalog | MAS-0124-YJ13 |
| Applications | Neut; Inhib; IP; WB; ELISA; Neut; FuncS |
| Host | Mouse |
| Reactivity | B. anthracis |
| Clonality | Monoclonal |
| Conjugations | Conjugation could be customized |
| Sub CAT. | Applications | Clone | Conjugations | Endotoxin Level | Size | Quantity | |
|---|---|---|---|---|---|---|---|
| MAS-0124-YJ13-A | Neut, Inhib, IP, WB, ELISA, Neut, FuncS | K07 |
Successfully!
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| MAS-0124-YJ13-B | ELISA, WB, Neut | 10B1 |
Successfully!
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Overview
Properties
Target
Overview
| Description | Clones K07 & 10B1 are Mouse monoclonal IgGs recognize B. anthracis Anthrax lethal factor. Both two could neutralize anthrax lethal toxin and have potential use for human anthrax infection. |
| Reactivity | B. anthracis |
| Applications | Neut; Inhib; IP; WB; ELISA; Neut; FuncS |
| Host | Mouse |
| Immunogen | Recombinant lethal factor. |
| Isotype |
K07: IgG2a 10B1: IgG2b kappa |
| Clonality | Monoclonal |
| Clone | K07; 10B1 |
| Dilutions | ELISA: 0.1-1000 ng/mL |
Properties
| Expression Host | HEK293F/CHO |
| Conjugations | Conjugation could be customized |
| Purification | Protein A/G affinity purified is the regular method |
| Purity | SDS-PAGE> 95% |
| Endotoxin Level | Endotoxin level could be customized |
| Form | Liquid (frequently-used) or lyophilized |
| Concentration | About 1mg/ml. There are differences between batches. Special concentration could be customized. |
| Sterility | 0.2 μM filtered |
| Buffer | See the Datasheet |
| Storage | See the Datasheet |
Target
| Target | B. anthracis Anthrax LF |
| Alternative Names | Anthrax lethal factor; LF; Anthrax LF; anthrax lethal toxin; LF; B. anthracis; Bacillus anthracis |
| Introduction | Anthrax toxin is a key virulence factor of anthrax, the chemical composition of three proteins: protective antigen (PA), lethal factor (LF) and edema factor (EF). LF or EF alone without toxicity, PA-LF complexes were formed after the PA and LF binding, called lethal toxin (Lethal Toxin, LeTx). |
| Organism | Bacteria |
| Related Disease | Anthrax |
| Infections Route | Cutaneous; Inhalation; Gastrointestinal; Injection |
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