Anti-C. psittaci LPS Monoclonal Antibody (Mouse mAb)

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Key Details
Catalog MAS-0524-YJ10
Applications ELISA
Host Mouse
Reactivity C. psittaci
Clonality Monoclonal
Conjugations Conjugation could be customized
Sub CAT. Applications Clone Conjugations Endotoxin Level Size Quantity
MAS-0524-YJ10-A ELISA R530
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MAS-0524-YJ10-B ELISA R620
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Overview
Properties
Target

Overview

Description Clone R530 and R620 are Mouse monoclonal IgGs recognizes C. psittaci LPS. R530 binds to Kdo(2→4)Kdo(2→4)Kdo epitope well and R620 binds to Kdo(2→4)Kdo, Kdo(2→8)Kdo, Kdo(2→4)Kdo(2→4)Kdo, Kdo(2→8)Kdo(2→4)Kdo well.
Reactivity C. psittaci
Applications ELISA
Host Mouse
Immunogen Kdo(2→4)[Kdo(2→8)]Kdo(2→4)Kdo(2→6)GlcNAc4P(1→6)GlcNAcol-BSA in PBS
Epitope R530 bound to the C. psittaci specific structures to a similar extent as R620 but exhibited lower affinity for all other antigens tested. Like R620, R530 did not differentiate between antigens containing the branched Kdo tetrasaccharide or the (2→4)-(2→4)-linked trisaccharide, but did bind to the 2→8-2→4-linked trisaccharide with weaker affinity than R620.
Isotype R530: Mouse IgG2a kappa
R620: Mouse IgG2b kappa
Clonality Monoclonal
Clone R530; R620
Dilutions ELISA: 0.1-1000 ng/mL

Properties

Expression Host HEK293F/CHO
Conjugations Conjugation could be customized
Purification Protein A/G affinity purified is the regular method
Purity SDS-PAGE> 95%
Endotoxin Level Endotoxin level could be customized
Form Liquid (frequently-used) or lyophilized
Concentration About 1mg/ml. There are differences between batches. Special concentration could be customized.
Sterility 0.2 μM filtered
Buffer See the Datasheet
Storage See the Datasheet

Target

Target C. psittaci LPS
Alternative Names Chlamydial lipopolysaccharide; C. psittaci; LPS; Chlamydia psittaci
Introduction The bacterial family Chlamydiaceae is comprised of two genera, Chlamydia and Chlamydophila, with a total of four species, C. psittaci, C. trachomatis, C. pneumoniae, and C. pecorum, all of which are pathogenic and obligatory intracellular bacteria that cause a variety of diseases in both animals and humans. Antibodies against specific lipopolysaccharide (LPS) structures play an important role in the clinical diagnosis of chlamydial diseases in medicine. The LPS of Chlamydiaceae are highly immunogenic and contains a family-specific epitope of the structure Kdo(2→8)Kdo(2→4)Kdo where Kdo is 3-deoxy-α-d-manno-oct-2-ulosonic acid.
Organism Bacteria; Chlamydia
Related Disease Schizophrenia
Infections Route Vertical propagation, Oral cavity, alimentary canal, Sexual Transmission
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