Key Details
| Catalog | MAS-0524-YJ43 |
| Applications | ELISA; WB |
| Host | Mouse |
| Reactivity | C. tetani |
| Clonality | Monoclonal |
| Conjugations | Conjugation could be customized |
Overview
Properties
Target
Overview
| Description | Clone C5 is a Human monoclonal IgG recognizes C. tetani Tetanus toxin HC. |
| Reactivity | C. tetani |
| Applications | ELISA; WB |
| Host | Mouse |
| Immunogen | The recombinant C-terminal domain of the tetanus toxin heavy chain (HC) |
| Epitope | C-terminal domain |
| Isotype |
mC5: Mouse IgG2a kappa mN2: Mouse IgG1 kappa mJ2: Mouse IgG2b kappa |
| Clonality | Monoclonal |
| Clone | mC5; mN2; mJ2 |
| Dilutions |
ELISA: 0.1-1000 ng/mL WB: 0.2-1 μg/mL |
Properties
| Expression Host | HEK293F/CHO |
| Conjugations | Conjugation could be customized |
| Purification | Protein A/G affinity purified is the regular method |
| Purity | SDS-PAGE> 95% |
| Endotoxin Level | Endotoxin level could be customized |
| Form | Liquid (frequently-used) or lyophilized |
| Concentration | About 1mg/ml. There are differences between batches. Special concentration could be customized. |
| Sterility | 0.2 μM filtered |
| Buffer | See the Datasheet |
| Storage | See the Datasheet |
Target
| Target | C. tetani Tetanus toxin HC |
| Alternative Names | HC; Heavy chain; B chain; Clostridium tetani toxin; Clostridium tetani; C. tetani; Tetanus Toxin; CTX; Clostridium tetani toxoid; Tentoxylysin |
| Introduction | The tetanus toxin protein has a molecular weight of 150kDa. It is translated from the tetX gene as one protein which is subsequently cleaved into two parts: a 100kDa heavy chain and a 50kDa light chain. The chains are connected by a disulfide bond. The B-chain binds to dissialogangliosides (GD2 and GD1b) on the neuronal membrane and contains a translocation domain which aids the movement of the protein across that membrane and into the neuron. |
| Organism | Bacteria |
| Related Disease | Tetanus |
| Infections Route | Wound |
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