Key Details
| Catalog | MAS-0524-YJ70 |
| Applications | WB; ELISA; FuncS |
| Host | Mouse |
| Reactivity | C. thermophilum |
| Clonality | Monoclonal |
| Conjugations | Conjugation could be customized |
| Sub CAT. | Applications | Clone | Conjugations | Endotoxin Level | Size | Quantity | |
|---|---|---|---|---|---|---|---|
| MAS-0524-YJ70-A | WB, ELISA, FuncS | m158 |
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Overview
Properties
Target
Overview
| Description | Clone m158 is a mouse monoclonal IgG recognizes C. thermophilum NSP1. |
| Reactivity | C. thermophilum |
| Applications | WB; ELISA; FuncS |
| Host | Mouse |
| Immunogen | C. thermophilum Nucleoporin NSP1 |
| Isotype | Mouse IgG2a |
| Clonality | Monoclonal |
| Clone | m158 |
| Dilutions |
ELISA: 0.1-1000 ng/mL WB: 0.2-1 μg/mL |
Properties
| Expression Host | HEK293F/CHO |
| Conjugations | Conjugation could be customized |
| Purification | Protein A/G affinity purified is the regular method |
| Purity | SDS-PAGE> 95% |
| Endotoxin Level | Endotoxin level could be customized |
| Form | Liquid (frequently-used) or lyophilized |
| Concentration | About 1mg/ml. There are differences between batches. Special concentration could be customized. |
| Sterility | 0.2 μM filtered |
| Buffer | See the Datasheet |
| Storage | See the Datasheet |
Target
| Target | C. thermophilum NSP1 |
| Alternative Names | NSP1; Nucleoporin NSP1; C. thermophilum; Chaetomium thermophilum |
| Gene ID | 18259477 |
| UniProt ID | G0SBQ3 |
| Introduction | Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm). NSP1 plays an important role in several nuclear transport pathways including poly(A)+ RNA, tRNA, pre-ribosome, signal recognition particle (SRP), and protein transport. |
| Organism | Fungus |
| Related Disease | C. thermophilum infection |
| Infections Route | Oral cavity, skin, alimentary canal |
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