Key Details
| Catalog | MAS-0124-YJ19 |
| Applications | Neut; ELISA; Cyt; DB; Inhib; WB; FC; IHC |
| Host | Human |
| Reactivity | B. anthracis |
| Clonality | Monoclonal |
| Conjugations | Conjugation could be customized |
Overview
Properties
Target
Overview
| Description | Clones A60J, 71F6B, 71F7B, 71F8B and 13A1 are Human monoclonal IgGs recognize B. anthracis Anthrax PA (Protective antigen). All these antibodies have human IgG constant regions. |
| Reactivity | B. anthracis |
| Applications | Neut; ELISA; Cyt; DB; Inhib; WB; FC; IHC |
| Host | Human |
| Immunogen | Recombinant PA |
| Isotype |
A60J, 13A1: Human IgG1; 71F6B: Human IgG2; 71F7B, 71F8B; Chimeric (chimpanzee/human) IgG1 kappa |
| Clonality | Monoclonal |
| Clone | A60J; 71F6B; 71F7B; 71F8B; 13A1 |
| Dilutions | ELISA: 0.1-1000 ng/mL |
Properties
| Expression Host | HEK293F/CHO |
| Conjugations | Conjugation could be customized |
| Purification | Protein A/G affinity purified is the regular method |
| Purity | SDS-PAGE> 95% |
| Endotoxin Level | Endotoxin level could be customized |
| Form | Liquid (frequently-used) or lyophilized |
| Concentration | About 1mg/ml. There are differences between batches. Special concentration could be customized. |
| Sterility | 0.2 μM filtered |
| Buffer | See the Datasheet |
| Storage | See the Datasheet |
Target
| Target | B. anthracis PA |
| Alternative Names | PA; PA83; Pag; PagA; Protective antigen; Bacillus anthracis; B. anthracis; B. anthracis Anthrax PA; Bacillus anthracis |
| Introduction | Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium, Bacillus anthracis-the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. |
| Organism | Bacteria |
| Related Disease | Anthrax |
| Infections Route | Cutaneous; Inhalation; Gastrointestinal; Injection |
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