Anti-B. anthracis PGA Monoclonal Antibody (Mouse mAb)

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Key Details
Catalog MAS-0124-YJ20
Applications ELISA; WB; IF; FuncS
Host Mouse
Reactivity B. anthracis
Clonality Monoclonal
Conjugations Conjugation could be customized
Sub CAT. Applications Clone Conjugations Endotoxin Level Size Quantity
MAS-0124-YJ20-A ELISA, WB, IF, FuncS B52
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Overview
Properties
Target

Overview

Description Clone B52 is a Mouse monoclonal IgG2b kappa recognizes B. anthracis PGA. It was raised against heat-killed encapsulated B. anthracis H9401. This antibody could inhibit activity of PGA in enhancing LT mediated cell cytotoxic activity. It has potential to protect from PGA-enhanced LT-mediated death and virulent spore challenge.
Reactivity B. anthracis
Applications ELISA; WB; IF; FuncS
Host Mouse
Immunogen Heat-killed encapsulated B. anthracis H9401
Isotype Mouse IgG2b kappa
Clonality Monoclonal
Clone B52
Dilutions ELISA: 0.1-1000 ng/mL

Properties

Expression Host HEK293F/CHO
Conjugations Conjugation could be customized
Purification Protein A/G affinity purified is the regular method
Purity SDS-PAGE> 95%
Endotoxin Level Endotoxin level could be customized
Form Liquid (frequently-used) or lyophilized
Concentration About 1mg/ml. There are differences between batches. Special concentration could be customized.
Sterility 0.2 μM filtered
Buffer See the Datasheet
Storage See the Datasheet

Target

Target B. anthracis PGA
Alternative Names B. anthracis PGA; Bacillus anthracis poly-gamma-D-glutamic-acid; B. anthracis; Bacillus anthracis; poly-gamma-D-glutamic-acid; PGA
Introduction Bacillus anthracis is the etiologic agent of anthrax-a common disease of livestock and, occasionally, of humans-and the only obligate pathogen within the genus Bacillus. B. anthracis is a Grampositive, endospore-forming, rod-shaped bacterium, with a width of 1. 0-1. 2 µm and a length of 3-5µm. It can be grown in an ordinary nutrient medium under aerobic or anaerobic conditions.
Organism Bacteria
Related Disease Anthrax
Infections Route Cutaneous; Inhalation; Gastrointestinal; Injection
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