Key Details
| Catalog | MAS-0124-YJ22 |
| Applications | WB; ELISA; FuncS |
| Host | Mouse |
| Reactivity | B. burgdorferi |
| Clonality | Monoclonal |
| Conjugations | Conjugation could be customized |
| Sub CAT. | Applications | Clone | Conjugations | Endotoxin Level | Size | Quantity | |
|---|---|---|---|---|---|---|---|
| MAS-0124-YJ22-A | WB, ELISA, FuncS | J572 |
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Overview
Properties
Target
Overview
| Description | Clone J572 is a Mouse monoclonal IgG2a kappa recognizes B. burgdorferi OspB C-terminus. It could kill spirochetes in the absence of phagocytes and without complement. |
| Reactivity | B. burgdorferi |
| Applications | WB; ELISA; FuncS |
| Host | Mouse |
| Immunogen | B. burgdorferi Outer surface protein B |
| Isotype | Mouse IgG2a kappa |
| Clonality | Monoclonal |
| Clone | J572 |
| Dilutions | ELISA: 0.1-1000 ng/mL |
Properties
| Expression Host | HEK293F/CHO |
| Conjugations | Conjugation could be customized |
| Purification | Protein A/G affinity purified is the regular method |
| Purity | SDS-PAGE> 95% |
| Endotoxin Level | Endotoxin level could be customized |
| Form | Liquid (frequently-used) or lyophilized |
| Concentration | About 1mg/ml. There are differences between batches. Special concentration could be customized. |
| Sterility | 0.2 μM filtered |
| Buffer | See the Datasheet |
| Storage | See the Datasheet |
Target
| Target | B. burgdorferi OspB |
| Alternative Names | OspB; outer surface protein B; Outer surface protein B; Borrelia burgdorferi; B. burgdorferi |
| Gene ID | 8319334 |
| Introduction |
OspB, is one of the major Outer Surface Proteins of the outer membrane of Borrelia burgdorferi, which is composed of various unique outer surface proteins (Osp) that have been characterized (OspA through OspF). The osp proteins are lipoproteins anchored by N-terminally attached fatty acid molecules to the membrane. They are presumed to play a role in virulence, transmission, or survival in the tick. Two of the major surface Ag of Borrelia burgdorferi, the 31-kDa OspA and 34-kDa OspB proteins, show a high degree of sequence similarity, are encoded by a 49-kb plasmid and share a common promoter, and are coordinately transcribed. |
| Organism | Spirochete; Bacteria |
| Related Disease | Lyme disease |
| Infections Route | Cutaneous |
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