Anti-EHEC Stx1B Monoclonal Antibody (Chimeric mAb)

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Key Details
Catalog MAS-0524-YJ8
Applications ELISA; WB; FC; Inhib
Host Human
Clonality Monoclonal
Conjugations Conjugation could be customized
Sub CAT. Applications Clone Conjugations Endotoxin Level Size Quantity
MAS-0524-YJ8-A ELISA, WB, FC cF1F6
Successfully!
MAS-0524-YJ8-B ELISA, WB, FC, Inhib cD2B7
Successfully!
Overview
Properties
Target

Overview

Description Clones cF1F6 and cD2B7 are chimeric monoclonal IgGs that recognize EHEC Stx1B. cD2B7 has the potential to interfere with the binding of Stx1B to cell surface ligands.
Applications ELISA; WB; FC; Inhib
Host Human
Immunogen Purified Stx1B
Isotype Both two clones are Chimeric (mouse/human) IgG1
Clonality Monoclonal
Clone cF1F6; cD2B7
Dilutions ELISA: 0.1-1000 ng/mL
WB: 0.2-1 μg/mL

Properties

Expression Host HEK293F/CHO
Conjugations Conjugation could be customized
Purification Protein A/G affinity purified is the regular method
Purity SDS-PAGE> 95%
Endotoxin Level Endotoxin level could be customized
Form Liquid (frequently-used) or lyophilized
Concentration About 1mg/ml. There are differences between batches. Special concentration could be customized.
Sterility 0.2 μM filtered
Buffer See the Datasheet
Storage See the Datasheet

Target

Target EHEC Stx1B
Alternative Names Shiga toxin 1 B subunits; Enterohaemorrhagic Escherichia coli Shiga toxin 1 subunit B; Enterohaemorrhagic Escherichia coli; Shiga toxin 1 subunit B; Stx1B; EHEC
Introduction Shiga toxin 1 produced by enterohaemorrhagic Escherichia coli is an AB₅ toxin that is involved in the life-threatening haemolytic-uraemic syndrome. The B subunits (Stx1B) are cell-binding subunits. Alpha-toxin (CPA or PLC) is produced by all C. perfringens strains, although toxinotype A strains usually produce higher amounts than the other toxinotypes
Organism Bacteria
Related Disease Haemolytic-uraemic syndrome
Infections Route Alimentary canal
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