Creative Biolabs is specializing in culturing 3D biology-based spheroid models. Our techniques in mimicking in vivo microenvironments and in vitro remodeling with 3D spheroids will assist you in a more efficient way of studying applications, including drug screening and tissue engineering.
Osteoblasts, the bone-forming cells, play a crucial part in the bone remodeling process by regulating resorption and formation, as well as transducing mechanical stimuli into biochemical signals through multiple mechanoreceptors. The calvaria is the top part of the skull and the upper part of the neurocranium. It covers the cranial cavity containing the brain and forms the main component of the skull roof. The 3D human calvarial osteoblast spheroid model is three-dimensional in vitro culture model that mimics the microenvironment of human bone tissue.
Fig 1. Schematic representation of the bone cell culture by 2D and 3D models.1
Bone defects caused by disease, surgery, or trauma are a major health problem worldwide. Bone tissue engineering is a raising valid alternative to conventional treatments to restore bone integrity. A calvarial osteoblast spheroid model, which allows cellular communication, can accurately resemble bone remodeling and/or the regeneration process.
Creative Biolabs provides a highly professional technical team mastering mature technology in the field of cultivating in vitro cells. Our 3D Human Calvarial Osteoblast Spheroid Model has unique advantages in the following aspects:
The cell lines we use are more representative of the in vivo bone microenvironment than immortalized cell lines.
Our culture methods can accurately represent tissue cells in vitro and monitor cell number, proliferation, response to stimuli, differentiation, drug metabolism, protein synthesis, etc.
Creative Biolabs has advanced 3D modeling technologies such as 3D bioprinting and microfluidics. Our professional team will choose the best way to generate the spheroids based on different models.
Our spheroid models can be applied in cancer research, stem cell research, drug discovery, and other customized research.
In addition to 3D Human Calvarial Osteoblast Spheroid Models, you may also be interested in:
Enriching our comprehensive array of 3D spheroid models, Creative Biolabs extends its offerings to encompass a series of specialized technical services, tailored to cater to the diverse research requirements of our clients. Feel free to contact us to explore the potential of our extensively customizable models and to receive a personalized quote.
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