3D Ex Vivo Human Digestive System Tissue Model Introduction

As a supplier of high-quality human-isolated biological tissue samples, Creative Biolabs provides our clients with the tissue sample solutions you need with strict standards and professional procurement procedures. Our global procurement network has extended our repository to include many difficult-to-access digestive tissue models.

Digestive System and Related Diseases

The digestive system is a complex system including the gastrointestinal tract and various auxiliary organs with secretory glands. As an anatomically continuous structure, it is responsible for the swallowing, digestion, absorption of nutrients and removal of metabolic waste. The interaction between the host and the resident bacteria is also mainly responsible for certain structures of the digestive system. The digestive system is the site of many acute and chronic diseases, including gastroenteritis, inflammatory bowel disease, or functional gastrointestinal disease. Colorectal cancer and gastric cancer are also among the most common malignancies. These diseases often have different pathological features and pathogenesis, and the development of reliable and correct preclinical models is crucial for the development of various diseases of digestive system organs and the development of intervention methods.

Limitations of Traditional Models

Traditional cell lines and animal models through two-dimensional culture have been widely used in the research of digestive system diseases. These models have made important contributions to the development of digestive system research, but they still have great limitations. It is difficult for most primary cells to establish effective immortal cell lines to cope with the culture span, and long-term cultured cell lines cannot accurately reproduce the complex genetic characteristics of primary tissues. Although animal models can overcome the limitations of cell lines, they are challenged by high cost, low throughput and complicated modeling techniques. Even more harshly, differences between species often lead to inefficient translation of disease progression and drug response into usable clinical research outcomes.

Fig 1. Comparison of murine, porcine, and human gastrointestinal tract anatomy and histology. (Ziegler, 2016)

Why Choose 3D Ex Vivo Human Digestive System Tissue Model?

• 3D Ex Vivo Human Bile Duct Tissue Model
• 3D Ex Vivo Human Esophagus Tissue Model
• 3D Ex Vivo Human Gallbladder Tissue Model
• 3D Ex Vivo Human Larynx Tissue Model
• 3D Ex Vivo Human Pharynx Tissue Model
• 3D Ex Vivo Human Palate Tissue Model
• 3D Ex Vivo Human Liver Tissue Model
• 3D Ex Vivo Human Pancreas Gland Tissue Model
• 3D Ex Vivo Human Parotid Tissue Model
• 3D Ex Vivo Human Salivary Gland Tissue Model
• 3D Ex Vivo Human Stomach Tissue Model
• 3D Ex Vivo Human Intestine Tissue Model

What Can We Provide?

Excellent experimental models will lay the foundation for successful research, and Creative Biolabs' service makes the once rare and precious 3D ex vivo human digestive system tissue model at your fingertips. All of our human tissues are validated with RNA Integrity Index scores to ensure maximum activity-dependent gene preservation and less RNA degradation. These well-processed and proprietary preserved human tissue samples will be delivered to you at the highest quality to maximize the success of your biologically relevant scientific research and drug discovery experiments. Please don't hesitate to contact us and discuss your needs with an expert.

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model