3D Tumor Spheroid Model Introduction

In contrast to conventional 2D cell culture approaches, tumor spheroids have emerged as a superior method for faithfully emulating the complex nature of solid tumors. Creative Biolabs is proud to present our state-of-the-art 3D tumor spheroid model, characterized by its exceptional spherical morphology, precise cellular arrangement, and remarkable chemical sensitivity.

Tumor spheroids for the study of tumor behavior. (Giannattasio, et al., 2015) Fig 1. Tumor spheroids for the study of tumor behavior.1

Traditional Models for Tumor Research

Notably, the absence of the macroscopic tumor structure, intricate tumor-stroma interactions, and the heterogeneous nature of the tumor microenvironment hinder the fidelity of 2D cell culture. For the commonly used animal tumor models, it is also imperative to acknowledge the considerable physiological and genetic disparities between animal and humans, alongside the profound ethical concerns entwined with animal experimentation.

Tumor spheroids. (Raghavan, et al., 2016)

3D Tumor Spheroid Model

Creative Biolabs’s 3D tumor spheroid model represents a dependable and high-throughput platform ideally suited for cancer research and drug screening endeavors. Through the implementation of our innovative technology, we have achieved enhanced cell-cell adhesion within the constructed multicellular tumor spheroids, resulting in the establishment of robust and well-defined structures.

Why Choose Creative Biolabs?

Tumor spheroids have garnered recognition as a superior alternative to conventional cell cultures, exhibiting a remarkable capacity to emulate the dynamic behavior of tumors. Choose Creative Biolabs, you will benefit from the following advantages

Creative Biolabs’s cutting-edge 3D spheroid model serves as an invaluable tool to delve into the intricate behavior of tumors, enabling comprehensive investigations into various facets of cancer research. We offer a diverse range of tumor spheroids constructed, thereby catering to your specific drug screening requirements.

Related Services

Creative Biolabs aspires to go beyond the provision of research models and samples. With our extensive experience and profound expertise in the field of biology, we eagerly anticipate a close collaboration with you. Our goal is to provide comprehensive one-stop services and enduring support. Please feel free to contact us for any needs.

References

Giannattasio, A.; et al. Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids. BMC Cancer. 2015, 15: 351.
Lee, J.M.; et al. Generation of uniform-sized multicellular tumor spheroids using hydrogel microwells for advanced drug screening. Nature. 2018, 8: 17145.
Raghavan, S.; et al. Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity. Oncotarget. 2016, 7(13): 16948.

Research Model

3D Biology Based Biomarker Discovery

3D Biology Based Drug Discovery and Development

3D Biology Based Toxicity Evaluation

Supporting Assays

3D Tumor Spheroid Model Introduction

Traditional Models for Tumor Research

3D Tumor Spheroid Model

Why Choose Creative Biolabs?

Related Services

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