Barrier Tissue On-a-Chip Model Introduction

Creative Biolabs specializes in the development of barrier tissue-on-a-chip models. Our models use microfluidic technology to mimic the structure and function of human barrier tissues in a controlled in vitro environment. Our research team with rich experience has developed a mature system to combine microfluidics with in silico modeling, enhancing the possibility for more accurate toxicity predictions.

Fig 1. Physiologically-based pharmacokinetic (PBPK) model of a human system. (Sakolish, 2016)

Barrier Tissue on-a-chip Model at Creative Biolabs

The barrier tissue on-a-chip model in Creative Biolabs enables the real-time study of barriers in a more physiological manner. Unlike static culture inserts, our microfluidic system allows for exposure to fluid flow and shear stress, which are crucial for vascular endothelium research. Talk to our experts about your specific requirement.

Fig 2. Structural assembly of the chip showing all layers of the device. (Walter, 2015)

Advantages of Our Barrier Tissue on-a-chip Model

Our microfluidic-based in vitro modeling offers significant advantages over traditional clinical testing methods. By enabling dynamic fluid flow, it promotes cell growth, differentiation, and polarization, resulting in more in vivo-like tissue behavior. Furthermore, the interconnected microfluidic chambers enable fluidic interaction and cell signaling, surpassing the limitations of static cultures and animal studies.

What Do We Provide?

Our newly developed barrier tissue-on-a-chip model is suitable for mass fabrication and allows you to further cultivate dynamic cells. We present you with a promising platform to study established in vitro models of tissue barriers under reproducible microfluid perfusion conditions.

See the barrier models here:

• Blood-brain Barrier (BBB) on-a-chip Model
• Skin on-a-chip Model
• Gastrointestinal Tract (GI tract) on-a-chip Model
• Kidney Renal Proximal Tubule (RPT) on-a-chip Model
• Blood Vessel on-a-chip Model
• Barrier on-a-chip Model

Related Services

Creative Biolabs, a global service provider in biotechnology, maintains its unwavering commitment to innovation by offering a comprehensive range of dependable services as delineated below. Our offerings cater to the diverse research needs of our clients around the world. If you are interested in our barrier tissue-on-a-chip models and the supportive assays we provide, please do not hesitate to contact us.

Related Sections:

• Single Organ-on-a-Chip Model Introduction
• Multiple Organs-on-a-Chip Model Introduction
• Customized Tissue-on-a-Chip Model Introduction
• Disease-on-a-Chip Model Introduction