3D Biology Based Ocular Toxicity Evaluation Services

Ocular toxicity assessment is an important test method that evaluates the potential toxicity of a product to the human eye. This test is commonly used during the research and development of cosmetics, pharmaceuticals, medical devices, and other products to determine if they cause damage or adverse reactions to the eye. Creative Biolabs provides 3D biology-based ocular toxicity assessment services to help clients determine the safety of product candidates.

Fig.1 Schematic comparison of human corneal structure with 3D triculture model structure.¹

Why Evaluate Products for Ocular Toxicity?

• Avoid possible risks. By evaluating the ocular toxicity of the product, it is possible to determine whether it is safe to use and reduce possible risks during use.
• Ensure full compliance with regulatory requirements. By evaluating the ocular toxicity of the product, it is possible to determine whether it is safe to use and reduce possible risks during use.
• Improve product quality. By conducting the ocular toxicity assessment, products that may cause eye damage or adverse reactions can be excluded, thereby accelerating product development.

3D Model Advantages for Ocular Toxicity Assessment

• No animal testing required. Traditional ocular toxicity assessment methods usually require animal testing, such as using mice or rabbits to test product irritation to the eyes. However, this approach has some disadvantages, such as animal testing that results in animal suffering and possible death. Organoids or 3D cell models based on cornea or retina are more ethical and moral.
• More predictive. Using 3D models for ocular toxicity assessment can more accurately reflect the physiological process and drug metabolism of the human eye, thereby better predicting the toxicity of the product to the human eye.
• Cost-effective. Animal testing also takes time and money, as animals need to be purchased and maintained, and results are difficult to generate in batches. In contrast, ocular toxicity assessment methods based on organoids or 3D cell models are less expensive and easy to achieve high-throughput assessment. This enables 3D eye models to be widely used in large-scale product screening and development.
• Faster results. Based on the cornea or retina-related organoids or 3D cell culture and testing, it is easy to implement and can get results faster, which is very helpful for shortening the development cycle of new products.

Featured 3D Model Services for Assessing Ocular Toxicity in Creative Biolabs

It should be noted that each drug candidate has its specific usage scenarios and uses, so it needs to be evaluated on a case-by-case basis. For different types of drug candidates, different evaluation methods and standards need to be selected. Creative Biolabs is a company specializing in drug discovery and development. Our scientific team has rich experience and technical strength in developing and providing 3D model for toxicity evaluation. We offer a range of 3D models for assessing the toxicity of your new ophthalmic drugs as listed below. Our team can also tailor comprehensive evaluation strategies to meet regulatory requirements, guaranteeing the precision and dependability of the results.

If you are looking for these models or other 3D eye models of your interests, please contact us and leave your specific needs in the inquiry box. Our experts will reply to you as soon as possible.

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