3D Biology Based Monocytes Chemotaxis Assay

Monocyte chemotaxis is intricately linked to a range of physiological and pathological phenomena, crucial for maintaining homeostatic circulation and development within the human body. At Creative Biolabs, we offer an extensive range of high-quality 3D biology-based monocyte chemotaxis assays to meet your specific needs.

Overview of Monocytes Chemotaxis Assay

Chemotaxis refers to the specific directional movement of cells along a gradient of chemotactic factors, demonstrating anatomical and temporal specificity. Furthermore, a robust and effective immune response relies heavily on the complex coordination of multiple cell types across temporal and spatial scales to appropriately react to injury and infection.

3D morphology of human monocytes migrating in collagen type I. Fig.1 3D morphology of human monocytes migrating in collagen type I.1

Unparalleled Expertise

By integrating traditional cell chemotaxis assays with advanced 3D models, our detection service aims to provide a stable and reproducible tool to accelerate the development of preclinical projects of worldwide scientists. Our one-stop monocyte chemotaxis solutions include:

Culture Environment

We offer an ideal monocyte chemotaxis testing model by setting up tissue-like collagen, fibrin gel, or microfluidic chip platforms according to the client's needs.

Customizable Designs

Chemotactic factors, cell types, concentrations, timeframes, and even complex interactions are all available tunable parameters.

Controlled Gradient

Optimized research models enable controlled and stable delivery of any chemical substances to cells, guiding cell movement in a simple and reproducible manner.

High-Precision Measurements

With cutting-edge imaging technology and experienced operators, we are capable of accurately distinguishing, quantifying, and tracking the movement trajectories of individual monocytes.

Procedural Overview

Our team of experts will comprehensively evaluate your experimental plan before we initiate it. Especially, detailed records of the experimental process, raw data, and an in-depth analysis report will be provided at the end of the project.

Procedural Overview.

Empowering Your Research Goals

By combining cutting-edge detection systems with advanced 3D models, Creative Biolabs evaluates monocyte migration under conditions that closely mimic the natural tissue microenvironment.

Our commitment to comprehensive service provision means that we can support you at every step of your scientific journey and go beyond offering specific types of assays. Choose Creative Biolabs for your analysis needs, and take your research to a higher level.

Reference

  1. Bzymek, Horsthemke, et al. " Real-time two- and three-dimensional imaging of monocyte motility and navigation on planar surfaces and in collagen matrices: roles of Rho. " Nature. 10 (2016): 25016.
Research Model

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