3D Biology Based Whole-Genome Sequencing (WGS) Service

Whole genome sequencing (WGS) has largely been used as a research tool to deliver comprehensive genetic analysis with the help of next-generation sequencing methods. Owning a knowledgeable team of well-trained bioinformaticians, Creative Biolabs can help you to dig out the critical information in your 3D biology model and accelerate your 3D biology-associated research project.

What Is WGS?

WGS is the technique of figuring out the full genomic DNA sequence or almost the entire sequence of an organism. Finding crucial biomarkers, describing cancer-causing mutations, detecting hereditary illnesses, and monitoring disease outbreaks have all been made possible by digging out genomic information. Thus, WGS has been regarded as a powerful tool for genomics research for the generation of massive amounts of data. With the maturation of WGS, the cost of WGS is decreasing.

Benefits of WGS

Because of its extensive, in-depth, and significant information, WGS provides a number of benefits.

3D Biology Based WGS

The in vivo milieu can be replicated by 3D biology models, which holds enormous potential for creating accurate tissue and disease models. When 3D biology models are used for WGS, more clinical-associated gene mutations could be discovered, and generated mutation distribution and frequency are more convincing and more identical to the actual situation in vivo. For disease-associated research, 3D biology based WGS will provide a more accurate diagnosis and help to find the biomarker or treatment target with high potential. In addition, it can aid in the selection of personalized therapy for individuals with cancer and help to find the available treatment target with a higher success rate.

3D Biology Based WGS Workflow

• Prepare your 3D biology derived samples for WGS.
• From the samples, the genomic DNA will be isolated and used to build a DNA library for sequencing.
• Then, a series of bioinformatics analyses can help us to better understand the covered information.
• The data can be visualized by a series of statistical analyses and associated figures.

Fig.1 The procedure of whole genome sequencing. (Creative Biolabs)

With well-established platforms and methods, Creative Biolabs can provide detailed, high-quality, and professional 3D biology based WGS service. We pledge to conduct every stage of the WGS according to the highest standards of science and to produce high-caliber research findings. For more details, please be free to contact us about your project.

3D Models Provided by Creative Biolabs

• 3D Spheroid Model
• Organ-on-a-chip Model
• 3D Ex Vivo Human Tissue Model
• 3D Precision-Cut Tissue Slice Model
• 3D Organoid Model

Related Sections:

• 3D Biology Based Multi-Omics Analysis Services
• 3D Biology Based Immune Response Analysis Services
• 3D Biology Based Target Analysis and Validation Services