3D Ex Vivo Human Bladder Tissue Model Introduction

Creative Biolabs has developed 3D ex vivo human bladder tissue model for global researchers. Our model empowers researchers to explore disease mechanisms, discover novel therapeutic targets, and evaluate treatment responses.

Human Bladder and Related Diseases

The primary function of the bladder is to store and eliminate urine by optimizing the bladder pressure regulated by the detrusor muscle in the bladder wall. Bladder disorders commonly occur as complications of various severe spinal cord injuries and neurodegenerative diseases. Although not life-threatening, they significantly impact the quality of life for patients.

Traditional Models

Several models have provided an in-depth understanding and direct experimental evidence of the pathways and intervention compounds for urinary tract diseases. However, animal models, especially commonly used rodents, exhibit significant differences from humans in terms of physiology, urine composition, and metabolism. In addition, in vitro human models often fail to replicate the complexity of the human bladder, hindering the development of various therapeutic approaches.

Fig.1 Bladder muscle cells under physiological stimuli. (Chae, 2022)

3D Ex Vivo Human Bladder Tissue Model

Creative Biolabs has successfully developed an advanced 3D ex vivo human bladder model system, which offers a unique tool to study intact human tissues and organs.

• Our ex vivo bladder tissue model is directly isolated and meticulously preserved to accurately represent the essential structures, physiological characteristics, and dynamic microenvironment of the human bladder.
• By maintaining organ-specific cues and biomechanical properties of relevant cell populations, this model serves as an invaluable research platform for human disease modeling and drug testing in basic research.

Our Services

The utilization of this model ensures the high availability of human bladder samples for rigorous pathological examination. Our model is specifically designed to study bladder physiological movements and can reliably deliver a high success rate for any endpoint analysis required in your research. Particularly, we have also developed other 3D ex vivo human urinary system tissue models listed below. For more detailed information, please click the links below.

• 3D Ex Vivo Human Bladder Contraction and Relaxation Model
• 3D Ex Vivo Human Ureter Relaxation Model
• 3D Ex Vivo Human Urethra Contraction Model
• 3D Ex Vivo Human Kidney Tissue Model

With our 3D ex vivo human bladder tissue model, you may conduct in-depth investigations into bladder function, disease mechanisms, and therapeutic interventions, ultimately advancing the understanding and treatment of bladder-related conditions. Contact us now to explore the endless possibilities offered by our advanced 3D model.

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model