3D Ex Vivo Human Ureter Relaxation Model Introduction

Creative Biolabs is dedicated to providing state-of-the-art 3D ex vivo human ureter relaxation models for global researchers. Our cutting-edge ex vivo model revolutionizes biomedical research, offering an unparalleled platform to study human organ functionalities in a controlled and realistic environment.

Ureter and Kidney Stone

The ureter is a tubular structure composed of muscular and mucosal layers located retroperitoneally. It extends from the renal pelvis to the trigone of the bladder. Its primary function is to transport urine and is aided by the valvular mechanism of the ureterovesical junction, which effectively prevents the backflow of urine from the bladder into the ureter. When kidney stones descend with the urine, they can become lodged at the narrow points of the ureter, causing ureteral colic and urinary obstruction. While these urinary stones are not life-threatening, they can lead to severe inflammation and a significant reduction in the quality of life.

Traditional Model for Ureter Relaxation Research

Due to significant physiological structural differences, traditional animal models are not ideal for studying the ureter. The human ureter has an average length of 26-28 centimeters and contains three narrow points prone to stone formation. Commonly used animal models, such as hamsters, exhibit notable anatomical differences in the ureter. Additionally, the types, quantities, and distributions of hormone receptors in experimental animals differ from those in the human body, increasing the likelihood of false-positive results in various tests.

Fig 1. Paravesical portion of ureter. (Harmeet, 2021)

What We Provide

Using ex vivo human ureter models would indeed be the optimal research tool for urinary tract studies. In fact, these models have almost no drawbacks apart from their relative rarity. Through close collaboration with hospitals and donation organizations worldwide, we efficiently and affordably deliver these exceptional samples to you.

Creative Biolabs 3D biology platform is available for evaluating the effects of your test substances on ureter relaxation (or contraction). Backed by cutting-edge technology, rigorous quality control, and unwavering dedication, our organ models provide unparalleled accuracy and reliability. Beyond 3D ex vivo human ureter relaxation model, we have also developed a few of 3D ex vivo human urinary system tissue models for global researchers. For more detailed information about these models, please click the links below. With our extensive expertise and unwavering commitment, we are confident in our ability to help you achieve your research goals. Please feel free to contact us about how we can promote your projects.

• 3D Ex Vivo Human Bladder Contraction and Relaxation Model
• 3D Ex Vivo Human Ureter Relaxation Model
• 3D Ex Vivo Human Urethra Contraction Model
• 3D Ex Vivo Human Bladder Tissue Model
• 3D Ex Vivo Human Kidney Tissue Model

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model