Neural Organoid Model

Due to ethical factors, the human brain sample is faced with the problem of insufficient sources, which limits our current knowledge of the central nervous system (CNS). Common animal models, even non-human primates, show several differences compared to the human brain. Thus, it is very challenging to study the development of the human CNS and related diseases. Creative Biolabs understands your research needs of neural disease and is committed to providing high-customizable 3D neural organoid models to customers, and aim to facilitate the progress of your preclinical drug research and development projects.

Advantages of Neural Organoid Models

The emergence of human neural organoids offers hope to study neurological diseases and understand the human brain more easily. In general, several significant advantages of neural organoid models have been demonstrated many times in current reports.

• Firstly, they can reproduce some critical characteristics of the in vivo brain, such as cellular distribution, physiological structure, electrical activities, and neuronal networks.
• They can generate multiple cell types and can reflect in vivo physiological microenvironment in vitro.
• In addition, the use of these models triggers fewer ethical issues than conventional animal models or fetal tissue samples.
• Such organoid models offer an invaluable platform to observe the development of the human brain because of the presence of tissue organization features.
• Much research has confirmed they are very promising to study atypical cellular, molecular, and genetic features.
• Furthermore, these models are an appropriate tool for testing new therapeutics in human cells and display great potential to develop cell replacement approaches to cure brain injury or disease.

Applications of Neural Organoid Models

Judging from the current research, neural organoid models are superior to other models in terms of enhancing the accessibility of developing human brain tissue. At present, they have been extensively applied in CNS development studies, disease modeling, mechanisms studies, personalized medicine, drug screening, regenerative approaches, and cellular transplantation, making noble contributions to the treatment of refractory neurological diseases. In recent years, some cutting-edge technologies have been injected into the disease field to further optimize such models. In the future, the ex vivo models will possess more development opportunities.

Fig.1 Applications of brain organoids (Qian, 2020)

Our Hot Neural Organoids

At Creative Biolabs, our robust human tissue procurement system has been built and runs smoothly, which can ensure the easy acquisition of various human tissues. To this day, we have mastered the 3D culture skills and successfully developed a broad range of 3D ex vivo organoid models including neural organoids, which have helped us win the unanimous recognition of customers. Our hot neural organoids are as follows.

Related Services

Apart from extensive organoid products in response to your research needs, we can also provide you with tailor-made services to accelerate your project. For more details, please feel free to contact us.

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