3D Ex Vivo Human Cardiac Contractility Model Introduction

3D ex vivo myocardial tissue models occupy an important position in cardiovascular medical research because of their simulated realistic environment and ease of analysis. Creative Biolabs has developed rich experience in tissue culture and 3D ex vivo model construction and can provide customized services related to the 3D ex vivo human cardiac contractility model, forming a library of methods for the construction of various conventional and difficult 3D ex vivo models.

Cardiac Contractility Model

Cardiac contractility refers to the ability of the ventricular muscle to change the size and speed of the heart contraction by relying only on its own characteristics. The basic idea of myocardial contractility model construction is to build an engineered heart tissue based on human pluripotent stem cells and regulate the blood supply required for cardiac pulsation with venous return and tissue metabolism, supporting the application in various cardiovascular disease studies.

Fig 1. Cardiac contractility is represented by directionally similar changes in both force and velocity. (Muir, 2020)

Traditional Myocardial Contractility Models

Drugs, diet, surgery, and physical induction are commonly used in the construction of traditional cardiac contractility models.

3D Ex Vivo Human Cardiac Contractility Model at Creative Biolabs

With the trend of precision medicine, Creative Biolabs is a perfect partner to develop a precise 3D ex vivo human cardiac contractility model in line with the basic concept of integrating personalized pathological information.

Our Services

Ex vivo human cardiovascular-related models are increasingly being used in precision medicine, Creative Biolabs offers a unique opportunity to support the construction of multiple 3D ex vivo human cardiovascular tissue models.

• 3D Ex Vivo Human Heart Failure Model
• 3D Ex Vivo Human Atrial Fibrillation Model
• 3D Ex Vivo Human Arrhythmogenic Disorders Model
• 3D Ex Vivo Human Chorionic Plate Arteries Model
• 3D Ex Vivo Human Aorta Tissue Model
• 3D Ex Vivo Human Artery Tissue Model

Creative Biolabs offers 3D ex vivo human cardiac contractility models that mimic real human cardiovascular pathology and omics landscape, providing a large-scale drug screening platform and essential resource for finding new targets and therapeutics for related diseases. Please contact us to discuss your project.

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model