Creative Biolabs provides high quality 3D ex vivo human chorionic plate arteries model to promote the process of global customers’ projects.
The chorionic plate arteries (CPA) play a crucial role in fetal development by supplying blood to the placenta. The arteries are responsible for transporting oxygen and nutrients from the mother's blood to the developing fetus. Any abnormalities in the function of these arteries can lead to complications during pregnancy. Preeclampsia and fetal growth restriction are two of the most significant complications associated with CPAs. In preeclampsia, the placenta's blood vessels do not develop correctly, leading to poor blood supply and oxygen delivery to the fetus. In contrast, fetal growth restriction occurs when the fetus's growth slows down, often due to poor blood flow through the placenta.
Fig 1. Human placenta blood flow. (Dellschaft, 2020)
Traditional models used in the study of CPA include animal models and 2D cell cultures. However, these models have significant limitations, including the inability to accurately replicate the complex microenvironment of the human body. Animal models are also subject to ethical concerns, and the use of animal models does not always translate to human physiology due to species differences which often leads to costly late clinical failures.
3D Ex Vivo Human Chorionic Plate Arteries Model
By studying the Chorionic Plate Arteries using 3D ex vivo human models, researchers can gain valuable insights into the pathogenesis of pregnancy complications and identify potential therapeutic targets. There are several advantages of using our 3D ex vivo human CPA model.
In answer to the demands of cardiovascular disease research, we have erected a comprehensive of human tissue models. For more detailed information, please click the links below.
With years of experience and advanced technology, Creative Biolabs is committed to accelerating global customers projects. Our extensive repositories enable us to meet urgent demands, and we offer customized human tissue to best fit the experimental design of our clients. For more information, please feel free to contact us.
References