The gastrointestinal tract (GI tract) on-a-chip model of Creative Biolabs can be used to study the gastrointestinal behavior of a wide variety of feed, food, and pharmaceutical products. Our human-based in vitro model could provide the key technologies necessary to speed up the drug discovery process by developing function-based human cell models that accurately capture and predict multi-organ complexity.
Our model is designed to reproduce the conditions in the lumen of the gastrointestinal tract by realistic mixing, transit of the meal, rate and composition of secretions, and removal of digested products and water. By integrating the two advanced biological and engineering techniques, we constructed integrated models of GI tract on-a-chip models with multiple types of human intestinal cells, maintaining normal physiological response and long cell viability in a defined medium with low serum condition.
The GI tract-on-a-chip highlights the potential applications in advancing our understanding of the GI tract's functions in drug absorptions, gut microbiome studies, nutrient absorptions and metabolism, and pharmacokinetic studies. Creative Biolabs provides customized models to revolutionize drug development, personalized medicine, and gastrointestinal research.
The gastrointestinal tract (GI tract) on-a-chip model of Creative Biolabs is designed accurately simulate and control the multi-compartmental processes in the lumen, which allows the testing of compounds under the same conditions or specifically modified conditions organ studies. Our high-end digestion model with high predictability and broad applicability will offer you a faster and more ethical alternative for drug metabolism and toxicity studies. View below for more barrier tissue-on-a-chip models.
Aligning with our expansive collection of barrier tissue-on-a-chip models, we present a suite of 3D biology-based assays, designed to bolster your preclinical research initiatives. Led by a proficient team of 3D biology experts, we are pleased to share comprehensive insights into our array of offerings. If you have specific requisites for our barrier tissue-on-a-chip models or an inclination to explore Creative Biolabs' comprehensive 3D biology services, please contact us for more information.