3D Ex Vivo Human Vasoconstriction Model Introduction

Creative Biolabs has successfully launched a powerful tool, 3D ex vivo human vasoconstriction model, for studying the pathogenic mechanisms of vasoconstriction-related diseases. We are pround of providing this high-quality model for researchers and pharmaceutical companies to accelerate their heart failure research and drug development process.

Vasoconstriction

Vasoconstriction is the narrowing of blood vessels due to the contraction of smooth muscles in the vessel walls. This process is essential for regulating blood flow and blood pressure, but dysfunction in the regulation of vasoconstriction is a significant contributor to various cardiovascular diseases. Hypertension results from an imbalance in the activity of vasoconstrictor and vasodilator signals, leading to a sustained increase in blood pressure. Similarly, atherosclerosis involves the formation of plaques within blood vessels, leading to reduced blood flow and increased vasoconstriction.

Fig 1. Human umbilical artery tissue. (Lorigo, 2022)

Traditional Models in Vasoconstriction Research

Traditional models, including animal models and in vitro cell culture systems, have been widely used to study vasoconstriction. However, these models have limitations in accurately recapitulating the complex physiological conditions of human vasoconstriction. Animal models often exhibit species-specific differences in vasoconstriction mechanisms, while in vitro cell culture systems lack the complex three-dimensional architecture and intercellular interactions found in vivo.

3D Ex Vivo Human Heart Failure Model

3D ex vivo human vasoconstriction model overcomes many of the limitations of traditional models, providing researchers with a more accurate representation of human vasoconstriction. Our 3D ex vivo human vasoconstriction model has many advantages, which including but not limited to:

Looking for More Models?

To accelerate the research in the field of cardiovascular disease, we have established a comprehensive collection and supply network. In addition to 3D ex vivo human vasoconstriction model, we have successfully developed multiple 3D ex vivo human cardiovascular tissue models. To learn more details about these models, please feel free to click the links listed below.

• Saphenous Vein Vasoconstriction
• Subcutaneous Resistance Arteries Vasoconstriction
• Coronary Arteries Vasoconstriction
• Cardiovascular Disease Research
• 3D Ex Vivo Human Heart Failure Model
• 3D Ex Vivo Human Atrial Fibrillation Model
• 3D Ex Vivo Human Arrhythmogenic Disorders Model
• 3D Ex Vivo Human Cardiac Contractility Model
• 3D Ex Vivo Human Vasodilation Model
• 3D Ex Vivo Human Ischemic Arteries Model
• 3D Ex Vivo Human Coronary Arteries Model
• 3D Ex Vivo Human Chorionic Plate Arteries Model
• 3D Ex Vivo Human Saphenous Veins Model
• 3D Ex Vivo Human Aorta Tissue Model
• 3D Ex Vivo Human Artery Tissue Model

Our Services

Creative Biolabs is dedicated to providing global researchers with a reliable and ethical supply of high-quality 3D ex vivo human cardiovascular models. Particularly, we have established an extensive network for the collection and supply of human tissue samples. Please feel free to contact us for more details on how we can promote your research.

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model