3D Ex Vivo Human Saphenous Veins Model Introduction

Creative Biolabs proudly provides a reliable and high-quality 3D ex vivo human saphenous veins model for research purposes as an essential tool in the study of cardiovascular disease and drug development processes.

Saphenous Veins

The saphenous veins are located just beneath the skin and have valves that prevent blood from flowing backward. They are responsible for carrying deoxygenated blood from the leg to the heart. Saphenous veins are important for blood circulation in the lower limbs and are often used in cardiac bypass surgery. However, they can also be subject to various diseases such as atherosclerosis, which can lead to heart failure. Thus, it is crucial to understand the underlying pathogenic mechanism to develop effective treatments.

Fig 1. Human saphenous veins after decellularization and recellularization. (Kuna, 2018)

Traditional Models in the Study of Saphenous Veins

Traditional models, such as animal models and in vitro cell culture models, have significant limitations in reproducing the complex physiological conditions of human Saphenous Veins. They are often unable to accurately mimic the responses of the human vasculature to various stimuli. Besides, species differences, lack of vascular complexity, and inadequate recapitulation of human physiology also hinder the development of new treatments.

Advantages of 3D Ex Vivo Human Saphenous Veins Model

Our 3D ex vivo human saphenous veins model has several advantages over traditional models. It is a physiologically relevant model that closely mimics human vascular physiology, allowing for more accurate testing of potential treatments. The model also provides a high level of reproducibility, which ensures that results are consistent across experiments.

Looking for More Models?

For the research on cardiovascular diseases, we have launched a comprehensive and high-quality acquisition-supply network to meet various expected needs.

• 3D Ex Vivo Human Heart Failure Model
• 3D Ex Vivo Human Atrial Fibrillation Model
• 3D Ex Vivo Human Arrhythmogenic Disorders Model
• 3D Ex Vivo Human Vasoconstriction Model
• 3D Ex Vivo Human Cardiac Contractility Model
• 3D Ex Vivo Human Vasodilation Model
• 3D Ex Vivo Human Ischemic Arteries Model
• 3D Ex Vivo Human Coronary Arteries Model
• 3D Ex Vivo Human Chorionic Plate Arteries Model
• 3D Ex Vivo Human Aorta Tissue Model
• 3D Ex Vivo Human Artery Tissue Model

Our Services

At Creative Biolabs, we are committed to advancing human biology research through early preclinical discovery. Our priority is to provide our clients with high quality and biologically faithful human tissue specimens. Contact us now for expert assistance with your research.

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• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model