3D Ex Vivo Human Coronary Arteries Model Introduction

Creative Biolabs proudly launches a powerful tool for studying the pathogenic mechanisms of coronary arteries-related diseases. We are committed to accelerating global researchers' projects in the field of heart failure research.

Human Coronary Arteries

The coronary artery system, which is responsible for supplying oxygenated blood to the heart muscle, is essential for heart function, and any disruptions to its structure or function can lead to serious health complications. Coronary artery disease is a common and deadly condition that affects millions of people worldwide. Research into the pathogenic mechanisms of coronary artery disease is critical in developing effective treatments and improving patient outcomes.

Left ascending coronary artery and left circumflex coronary artery.Fig 1. Left ascending coronary artery and left circumflex coronary artery. (Yoon, 2020)

Traditional Models for Studying Coronary Arteries

Traditional models for studying coronary artery diseases, such as animal models and 2D cell cultures, have significant limitations in terms of accuracy and relevance to human disease. Animal models may not accurately reflect the complex physiology of human coronary arteries, while 2D cell cultures lack the spatial and mechanical cues necessary for modeling physiological conditions.

Advantages of 3D Ex Vivo Human Coronary Arteries Model

Our 3D ex vivo human coronary arteries model offers several advantages over traditional models, which including but not limited to:

3D Ex Vivo Human Coronary Arteries Model

Looking for Other Models?

To meet the demands of cardiovascular disease research, we have established a series of ex vivo human cardiovascular tissue models. For more detailed information, please click the links below.

Our Services

Creative Biolabs delivers a comprehensive 3D ex vivo human coronary artery model for the study of coronary artery-associated diseases. Our team of specialists will guide the research process and is available to provide professional support throughout the whole process. We welcome inquiries from global clients and are committed to providing exceptional customer service.

References

  1. Yoon, S.; et al. A patient-specific 3D+t coronary artery motion modeling method using hierarchical deformation with electrocardiogram. Sensors. 2020, 20: 5680.
  2. Yu, Y.; et al. Outcomes of middle cardiac vein arterialization via internal mammary/thoracic artery anastomosis. PLOS ONE. 2013, 8(11): e80963.
  3. Liu, J.; et al. Coronary Tortuosity overestimate the FFR measurement in stenotic coronary artery model. Research Square. 2021, 3: 144020.
Research Model

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