Creative Biolabs proudly launches a groundbreaking tool in cardiovascular research with an innovative and sophisticated method for studying the pathogenic mechanisms and potential treatments for various cardiovascular diseases.
Vasodilation is a physiological process that involves the relaxation of smooth muscles in blood vessels, resulting in an increase in blood flow and oxygen delivery to various organs and tissues in the body. Numerous factors can affect vasodilation, such as age, gender, lifestyle, and genetic predisposition. The study of vasodilation and its mechanisms is critical in understanding and treating various cardiovascular diseases, such as hypertension, coronary artery disease, and heart failure. Coronary artery disease (CAD) is a leading cause of heart failure and death worldwide. The pathological mechanisms that underlie CAD are complex and multifaceted, making it challenging to develop effective treatments.
Fig 1. Human artery vasodilation and vasoconstriction. (Brinton, 2018)
Traditional models for studying vasodilation include animal models, cell culture models, and in vivo imaging techniques. However, these models have several limitations, such as the lack of tissue specificity, the inability to mimic the complex interactions between different cell types and tissues, and the ethical concerns surrounding the use of animals in research. In addition, some of these models may not accurately represent the human cardiovascular system, and their results may not be directly applicable to human disease.
Our 3D ex vivo human vasodilation model offers several advantages over traditional models, enabling discoveries to move more quickly from the laboratory to clinical applications.
To address the demands of cardiovascular disease research, we have established an all-encompassing collection and supply network of human tissue models.
Creative Biolabs is committed to providing researchers high-quality 3D ex vivo human vasodilation models. We have established a far-reaching network for the collection and supply of human tissue samples, thereby allowing for genuine human biology research during the early stages of preclinical discovery. Please feel free to contact us for more detailed information on how we can assist your projects.
Reference