3D Ex Vivo Human Esophagus Tissue Model Introduction

Creative Biolabs provides state-of-the-art 3D ex vivo human esophagus tissue models that preserve the complex architecture and function of the human esophagus. These high-quality human biological samples can meet the experimental needs of the entire drug development and testing process, providing feasible solutions and expanding infinite possibilities for your research project.

Esophagus and Related Diseases

The esophagus, a slender and lengthy conduit, links the pharynx atop and the gastric cardia beneath. Its chief function is to facilitate the passage of food into the stomach by means of its segmented and longitudinal muscular layers. However, an assortment of maladies can afflict the esophagus, including gastroesophageal reflux, esophagitis, Barrett's esophagus, and esophageal cancer, posing a threat to the well-being of numerous patients.

Limitations of Traditional Models

Conventional cell and animal models have been commonly used to explore esophageal diseases. Nonetheless, these models have inherent limitations that impede the translation of their findings into clinical settings. For instance, animal models may not accurately replicate human disease progression or drug response due to inter-species disparities. Likewise, cell models frequently have a limited capacity to mimic the three-dimensional architecture and cellular composition of the human esophagus.

Fig 1. Esophageal research models. (Whelan, 2018)

Fig 2. Image of rat and human tissue staining. (Chen, 2008)

More Ex Vivo Human Digestive System Tissue Models at Creative Biolabs

Based on extensive human tissue supply network, Creative Biolabs provides excellent 3D ex vivo human esophagus tissue models for research purposes. We isolate and preserve cells and extracellular matrix in their native state. The tissue is then processed to create a 3D structure that replicates the in vivo environment of the esophagus, including the presence of various cell types, extracellular matrix components, and physiological forces. We are also able to deliver fresh unprocessed human esophageal tissue to maximize its natural properties and functions. The tissue models are also customizable, allowing researchers to select tissue samples based on specific disease states, demographics, and other factors, and we will guarantee the legality, compliance, and delivery of relevant donor data with these tissue samples.

We provide you with a rare and reliable tool for digestive system diseases, our service include:

• 3D Ex Vivo Human Bile Duct Tissue Model
• 3D Ex Vivo Human Esophagus Tissue Model
• 3D Ex Vivo Human Gallbladder Tissue Model
• 3D Ex Vivo Human Larynx Tissue Model
• 3D Ex Vivo Human Pharynx Tissue Model
• 3D Ex Vivo Human Palate Tissue Model
• 3D Ex Vivo Human Liver Tissue Model
• 3D Ex Vivo Human Pancreas Gland Tissue Model
• 3D Ex Vivo Human Parotid Tissue Model
• 3D Ex Vivo Human Salivary Gland Tissue Model
• 3D Ex Vivo Human Stomach Tissue Model
• 3D Ex Vivo Human Tongue Tissue Model
• 3D Ex Vivo Human Intestine Tissue Model

3D ex vivo human esophageal tissue models provide an innovative platform for studying esophageal diseases, and we have made an otherwise rare model readily available, so please don't hesitate to contact us for any needs.

Related Sections:

• Ex Vivo Human Genitourinary Tissue Model
• Ex Vivo Human Skin System Tissue Model
• Ex Vivo Human Urinary System Tissue Model
• Ex Vivo Neurological System Model
• Ex Vivo Human Digestive System Model
• Ex Vivo Human Musculoskeletal System Tissue Model
• Ex Vivo Human Respiratory System Tissue Model
• Ex Vivo Human Endocrine System Tissue Model
• Ex Vivo Human Cardiovascular Tissue Model