3D Ex Vivo Human Palate Tissue Model Introduction

Creative Biolabs has launched a human tissue sample collection and supplement platform, bringing true human biology to early clinical discovery. Whether your team hopes to further explore palate-related pathological knowledge, or to develop new therapies and ensure the safety of the digestive system, we will try our best to provide you with the safest and most effective ex vivo human tissue models, avoiding costly late failures.

Palate and Related Diseases

The palate, a complex and vital structure that separates the oral and nasal cavities in humans, plays an essential role in speech, swallowing, and breathing. Unfortunately, Palate diseases such as cleft palate, palatal tumors, and numerous infections significantly impair an individual's quality of life. Despite the high prevalence of Palate diseases, the underlying pathogenic mechanisms remain poorly understood, and current research has been unable to unravel the intricate interactions involved.

Fig 1. Anatomy of the palatal suture. (Shibusawa, 2021)

Why Choose 3D Human Palate Tissue Model?

Limitations of Traditional Models

Traditional animal and cell models have been the primary tools for studying palate diseases, but their inability to replicate the complex structural and functional characteristics of human Palate tissue has resulted in limited success in predicting drug efficacy and toxicity in clinical trials. Moreover, these models are inadequate in simulating the complex cell-matrix interactions that are crucial in the development of palate diseases. Differences between animal models and humans have also led to the failure of many research results to be translated into clinical results.

3D Human Palate Tissue Model

Ex vivo models have emerged as a promising alternative for taste studies. These models provide a more physiologically relevant experimental setting. The well-preserved anatomical structure and function perfectly reproduce the state of pathology or physiology of human tissue, which provides the possibility for the research and drug development of specific human diseases. Our cutting-edge 3D ex vivo human palate tissue model is an outstanding and comprehensive tool for palate disease investigation and intervention approach development.

Fig 2. Human palatal arch tissue model with landmarks. (Oxilia, 2021)

More 3D Ex Vivo Human Digestive System Tissue Models at Creative Biolabs

To ensure the highest quality of human palate tissue samples, our procurement and supply network operates with strict ethical standards, and each sample is collected according to standard operating procedures. A detailed review process ensures that each sample has strict confidentiality and security, and is supported by comprehensive clinical information and relevant data. These freshly collected, highly reproducible and physiologically relevant tissue models will be processed, preserved and delivered to customers using our state-of-the-art, customizable technology, enabling researchers to study palate diseases more comprehensively and accurately. Our team of experts is always available to provide professional support and advice on experimental design and data analysis. Our procurement and supply network, combined with our expertise in tissue processing and modeling, makes us an ideal partner for researchers looking to advance the understanding and treatment of digestive system diseases. Our 3D human tissue model will cover:

At Creative Biolabs, we are committed to providing researchers with the best possible tools and resources to achieve their research goals. Contact us today for any of your Palate research needs.

Reference

Shibusawa, N.; et al. Mathematical modeling of palatal suture pattern formation: morphological differences between sagittal and palatal sutures. Scientific Reports. 2021, 11: 8995.
Oxilia, G.; et al. Exploring directional and fluctuating asymmetry in the human palate during growth. Physical Anthropology. 2021, 175: 847-864.

Research Model

3D Biology Based Biomarker Discovery

3D Biology Based Drug Discovery and Development

3D Biology Based Toxicity Evaluation

Supporting Assays

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