3D Ex Vivo Human Gallbladder Tissue Model Introduction

Creative Biolabs has the capability to deliver human 3D ex vivo tissue models for gallbladder-related research, including fresh-frozen unprocessed models, custom preservation protocols processed models or difficult-to-obtain pathology samples.

Gallbladder and Related Diseases

The gallbladder is located behind the liver and is responsible for storing, concentrating and excreting bile in due course to participate in the digestive process. Anatomically, the inner surface of the gallbladder has well-developed folds and contains rich blood vessels, connective tissue, lymphatic vessels and elastic fibers.

The most common gallbladder disorders include cholecystitis, tumors, and gallstones. These Gallbladder-related ailments have long been an enigma in the medical field, and the underlying pathogenic mechanism remains elusive due to limited research models. The traditional clinical methods of gallbladder disease are only intervened by resection. Although effective, they often cause serious interference with the life of patients after recovery.

Why Choose 3D Ex Vivo Human Gallbladder Tissue Model?

Conventional animal and cell models have proven to be insufficient in replicating the complexities of the gallbladder, which hinders progress in understanding the disease. However, ex vivo models have emerged as promising alternatives due to their numerous advantages.

Ex vivo models are capable of preserving the natural environment of the gallbladder, which allows for a more accurate representation of the disease progression or physiological structure, which allows researchers to study the disease in a more comprehensive and realistic manner, leading to a deeper understanding of the pathogenic mechanism. Additionally, ex vivo models offer a higher degree of control over the experimental conditions, which eliminates many of the confounding factors present in in vivo models.

Fig 1. Gallbladder-related research model. (Yuan, 2021)

3D Ex Vivo Human Gallbladder Tissue Model at Creative Biolabs

Creative Biolabs has developed a mature, stable, and comprehensive 3D ex vivo human gallbladder tissue donor network, enabling us to provide exceptional tissue models and related services to researchers seeking to better understand gallbladder-related diseases.

We will uphold a professional and strict attitude to provide our clients with high-quality human tissue models that have been verified with reviewed clinical data. Through extensive collaboration with hospital procurement sites around the world, our network of tissue donors consists of diverse populations with diverse medical histories, and these pathologically reviewed models allow for the study of different subtypes of gallbladder disease. This diversity ensures that our tissue models are accurately representative of the broad population, which increases the relevance of research conducted using our models.

More 3D Ex Vivo Human Digestive System Tissue Models at Creative Biolabs

Our team of experts works tirelessly to provide researchers with a full suite of services, including tissue preparation, preservation and analysis. Through our services, scientists around the world have access to reliable and accurate data that can help to gain a deeper understanding of gallbladder-related diseases and use this knowledge for drug development. Our 3D ex vivo human gallbladder tissue models and related services provide an invaluable resource and precious tool for users seeking to improve their understanding of gallbladder disease or drug development.

Our comprehensive for digestive system diseases research model includes:

With our mature and stable tissue donor network, we have the ability to provide excellent tissue models and related services to global researchers and will be delivered quickly in the way that best suits your experimental design, so please don't hesitate to contact us for any needs.

Reference

Yuan, B.; et al. Patient-derived organoids for personalized gallbladder cancer modeling and drug screening. Clinical and Translational Medicine. 2021, 12: 678.

Research Model

3D Biology Based Biomarker Discovery

3D Biology Based Drug Discovery and Development

3D Biology Based Toxicity Evaluation

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