Als Disease-on-a-Chip Model Introduction

Creative Biolabs has put efforts into the production of the ALS disease-on-chip model to meet the need for the development of new, effective therapies for treating amyotrophic lateral sclerosis (ALS) disease. The models in our lab will streamline drug development studies, subsequently enhancing candidate drug selection for a wide variety of neuromuscular disorders.

Formation of ALS Disease-on-a-chip Model

The microfabricated motor unit mimic device uses polydimethylsiloxane (PDMS) microchannels to form four sites on a single chip, each of which includes medium reservoirs, gel injection ports, and compartments for culturing neuron spheroids.

Fig 1. Compartmentalized design of a human motor unit on a chip microfluidic device. (Osaki, 2018)

Why Creative Biolabs?

ALS disease-on-a-chip model has rapidly evolved in recent years and will further your understanding of NMJ defects in ALS. ALS Chip model at Creative Biolabs incorporates patient-derived induced pluripotent stem cells (iPSCs), enabling the generation of patient-specific disease models. Researchers can develop more effective and precise treatment strategies with our ALS Chip.

Besides the ALS disease-on-a-chip model, there are alternative options worth considering:

Related Services

Enhancing our comprehensive array of disease-on-a-chip models, Creative Biolabs now offers a suite of 3D biology-based services as listed below, to help study the pathophysiological mechanism and develop promising therapeutic strategies to a larger extent. Please feel free to contact us at any time to discuss about your project for more rapid success.

Related Sections:

• Single Organ-on-a-Chip Model Introduction
• Multiple Organs-on-a-Chip Model Introduction
• Barrier Tissue On-a-Chip Model Introduction
• Customized Tissue-on-a-Chip Model Introduction
• Disease-on-a-Chip Model Introduction