Hepatitis B-on-a-Chip Model Introduction

Creative Biolabs has demonstrated the long-term maintenance of differentiated human hepatocytes as well as the utility of our hepatitis B-on-a-chip model. Our in vitro human hepatocyte culture systems mimic the environment and cellular architecture of the liver and can be used for diverse liver biology studies and liver-related disease research.

Glance at Our Hepatitis B-on-a-chip Model

The in vitro hepatitis B-on-a-chip model uses a microfluidic cell culture platform with a continuous perfusion system and hepatitis B virus (HBV) replication cycle. Hepatocytes cultured in the liver sinusoid on a chip with a perfusion system are infected with HBV. HBV replicates in the hepatocytes and is secreted from the host cell. The expression of HBV proteins and duplication of HBV in septic cells can be found through immunofluorescence staining or polymerase chain reaction (PCR) analysis, singly.

Fig 1. Hepatitis B-on-a-chip Model. (Kang, 2017)

Advantages of Our Hepatitis B-on-a-chip Model

Applications of Hepatitis B-on-a-chip Model

• Represent analysis of the consequences of an HBV infection accurately.
• Facilitate long-term liver-related disease studies successfully.
• Capable of being elongated to longitudinal investigations containing viral infections of primary human hepatocytes.

Why Choose Us?

Our hepatitis B-on-a-chip model can also assist you in numerous applications in other liver-related research and drug development and can be used for long-term studies of the consequence of a Hepatitis B virus (HBV) infection to human hepatocyte physiology.

Alongside the hepatitis B-on-a-chip model, there are additional models at Creative Biolabs that could be of interest:

Related Services

Drawing upon our cutting-edge technology platform and a team of seasoned scientists, Creative Biolabs pioneers the forefront of 3D biology. Alongside these disease-on-a-chip models, we provide expertly crafted and customized assay services to our esteemed global clients. We extend a warm invitation for you to connect with us, as we believe that our collaboration would drive substantial advancements of your research.

Related Sections:

• Single Organ-on-a-Chip Model Introduction
• Multiple Organs-on-a-Chip Model Introduction
• Barrier Tissue On-a-Chip Model Introduction
• Customized Tissue-on-a-Chip Model Introduction
• Disease-on-a-Chip Model Introduction