Alzheimer's Disease-on-a-Chip Model Introduction

Creative Biolabs' in vitro Alzheimer's disease-on-a-chip model, combining real-time investigation and brain-like structure, has the potential to increase your understanding of neural physiology, the potential neurotoxic and biological effects of chemical agents, and the specific cellular mechanisms of neurological disease progression.

Formation of Alzheimer's Disease-on-a-chip Model

The Alzheimer's disease-on-a-chip model fabrication and neural network formation was constructed with three layers, including a culture chamber layer consisting of polydimethylsiloxane (PDMS). The configurational tier part with space, inside the culture wells grips the neurospheroids, and points the neurite outcome in the channels to make certain total neural network construction. The PDMS provides a chamber layer for culture.

Schematic illustration of the design and fabrication of the AD-on-a-chip model.Fig 1. Schematic illustration of the design and fabrication of the AD-on-a-chip model. (Liu, 2022)

Advanced Alzheimer's Disease-on-a-chip Model at Creative Biolabs

  • Generating a highly accurate brain model with network formation.
  • Enclose a real-time neural network keeping track of the platform to research the biochemical results of therapeutic molecules.
  • Provide a real-time monitoring system that could be used for tracking the effect of pathological factors and drug screening with time.
  • Provide an inexpensive and rapid analytical technology to simulate the bio-physiological interactions of cells.

Applications of Alzheimer's Disease-on-a-chip Model

The Alzheimer's disease-on-a-chip model is considered as a promising alternative for in vitro models of neurodegenerative diseases such as Alzheimer's disease, contributing to the study of drug discovery and cell-protein interactions in the brain. The potential applications include but not limited to:

  • Exam leading mechanisms fundamental brain disease pathology and cell–molecule interactions.
  • Inaugurate and regulate other neurological disease in vitro models.
  • Examine pathological variations and cell-protein interactions.
  • Drug discovery and the development of novel therapeutic methods.
  • Allow the high-throughput pharmaceutical testing, basic science development. and specific superintendence of culture circumstances.

Why Choose Us

Our Alzheimer's disease-on-a-chip model will be able to bridge the gap between conventional 2D culture and animal models for the study of sophisticated brain structures and pharmaceutical applications, which can assist you in studies such as the screening of new therapeutics and drugs.

In addition to the Alzheimer's disease-on-a-chip model, we provide several alternative models that might be suitable for your applications:

Related Services

Beyond our wide range of disease-on-a-chip models, Creative Biolabs introduces an assortment of 3D biology-based technical services, meticulously crafted to meet the diverse research needs of our global clients. With our unwavering dedication and expertise, we are aiming at to be your dependable partner, offering comprehensive pre-sales and after-sales assistance. Reach out to us anytime to accelerate the progress of your project.

Reference

  1. Liu, N.; et al. A real-time sensing system for monitoring neural network degeneration in an Alzheimer's disease-on-a-chip model. Pharmaceutics. 2022, 14(5): 1022.
Research Model

Related Sections:

USA
UK
Germany
Inquiry Basket
Copyright © Creative Biolabs. All Rights Reserved.
Top