Bone-on-a-Chip Model Introduction

Bone remodeling is a dynamic and continuous process required for the maintenance of the skeleton architecture which response to mechanical stimuli. Creative Biolabs' biomimetic bone-on-a-chip model contributes to a better understanding of the processes related to bone formation and remodeling. We have developed a high-throughput biomimetic bone-on-a-chip platform that recapitulates the physiologically functional bone unit, using a well-plate-based system, which in turn can be used for the study of strategies.

Fabrication Process of Our Bone-on-a-chip Model

Bone-on-a-chip model is fabricated using well plate-based hydrogel-incorporating gel units, which are advantageous for a variety of cell biology applications and high-throughput analysis. The abstract graphic may help you understand our process from A to Z.

Fig 1. Fabrication process of bone-on-a-chip platform. (Creative Biolabs)

Advantages of Creative Biolabs' Bone-on-a-chip Model

Why Choose Us?

Due to the higher complexity of the bone tissue compared to other tissues, microfluidic technologies, especially bone-on-a-chip models, have yet very few reviewed worldwide. Creative Biolabs has recapitulated both the physical and chemical characteristics of the bone microenvironment, and improved the progress made in vascularization and innervation of bone-on-a-chip organotypic model systems. We have further developed bone metastasis and microfluidic devices designed to model the discrete stages of this process, as well as signaling pathways associated with it. Our novel bone-on-a-chip model is suitable to study processes related to bone regeneration and will assist you in relative research.

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Related Services

Supplementing our extensive organ-on-a-chip models, we introduce customized 3D biology based supporting assays. With a team of seasoned scientists adept in 3D biology, we are thrilled to provide thorough information about our offerings to elevate your preclinical drug discovery pursuits, spanning both service and product aspects. If you have any special needs in our organ-on-a-chip models or be interested in learning more about Creative Biolabs' 3D biology services, please feel free to contact us for more details.

Related Sections:

• Single Organ-on-a-Chip Model Introduction
• Multiple Organs-on-a-Chip Model Introduction
• Barrier Tissue On-a-Chip Model Introduction
• Customized Tissue-on-a-Chip Model Introduction
• Disease-on-a-Chip Model Introduction